Postdoctoral Researcher in Chemical Biology: The University of Antwerp is seeking a full-time postdoctoral researcher in the Department of Pharmaceutical Sciences. This position focuses on protease research, specifically the development of Granzyme B ligands and probes, in collaboration with leading research groups. The successful candidate will contribute to groundbreaking research aimed at improving cancer treatments through targeted immune responses.
Postdoctoral Researcher in Chemical Biology and Drug Discovery
Designation
Postdoctoral Researcher in Chemical Biology and Drug Discovery
Research Area
- Chemical Biology
- Drug Discovery
- Protease Research (Granzyme B)
Location
University of Antwerp, Campus Drie Eiken, Antwerp, Wilrijk, Belgium
Eligibility/Qualification
- Doctoral degree (PhD) from a non-Belgian institution in Pharmaceutical Sciences, Chemistry, Biochemistry, Biomedical Sciences, Medicine, or (Bio-)Engineering Sciences.
- Not resided, studied, or worked in Belgium for more than 24 months in the past 3 years.
- Comply with eligibility conditions for junior FWO postdoctoral fellowships and/or MSCA European Postdoctoral Fellowships.
- Expertise in protein expression, purification, and high-resolution structure determination is an asset.
- Strong communication skills; fluent in academic English (speaking and writing).
- Quality-oriented, team-oriented, creative, and cooperative.
Job Description
The postdoctoral researcher will be involved in:
- Production and purification of Granzyme B via an in-house recombinant expression system.
- Structural biology, including elucidation of GRZB-probe co-complexes and determination of binding modes using macromolecular X-ray crystallography.
- Kinetic characterization of probes with binding parameters determination through various assays.
- Synthesis and optimization of GRZB probes for further applications.
- Co-supervision of PhD students and grant applications for postdoctoral fellowships in the related field.
How to Apply
Interested candidates can apply through the University of Antwerp’s online job application platform. Applicants must submit:
- A detailed CV
- A letter of motivation
- Contact details of two referees
Applications are accepted until March 13, 2025 (by midnight Brussels time).
Last Date to Apply
March 13, 2025
Contact Information
For questions about the online application form, refer to the frequently asked questions or email jobs@uantwerpen.be. For questions about the profile and responsibilities, contact Prof. Ingrid De Meester (ingrid.demeester@uantwerpen.be) or Prof. Pieter Van der Veken (pieter.vanderveken@uantwerpen.be).
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