Postdoctoral Researcher in Enzyme Characterization: We are seeking a qualified postdoctoral researcher to join our EU-funded team focused on the genetic engineering of bacteria to develop sustainable cell factories. This role will emphasize the characterization and engineering of enzymes for converting single-carbon feedstocks into valuable multi-carbon compounds.
Postdoctoral Researcher in Enzyme Characterization and Engineering
Designation:
Postdoctoral Scientist
Table:
| Details | Information |
|---|---|
| Type | Academic Staff |
| Contract Hours | 38 hours per week |
| Location | Leiden, Netherlands |
| Salary Range | €3,546 – €5,538 gross per month |
| Contract Duration | Fixed-term from 01-05-2026 to 31-07-2028 |
| Application Deadline | 5 February 2026 |
Research Area:
- Enzyme Engineering
- Metabolic Engineering
- Synthetic Biology
Location:
Leiden, Netherlands
Eligibility/Qualification:
- PhD in Biochemistry, Biotechnology, Synthetic Biology, Microbiology, or a related discipline.
- Practical experience in:
- Heterologous protein production
- Purification and characterization using spectrophotometric or LC-MS-based assays.
- Background in enzyme engineering through:
- Targeted or random mutagenesis
- High-throughput screening
- Directed evolution
- Growth coupling
- Knowledge of enzyme structure analysis via crystallography or cryo-EM techniques is advantageous.
- Interest in metabolic engineering and synthetic biology.
- Ability to work collaboratively in an international project with readiness for travel.
Job Description:
The successful candidate will focus on characterizing and engineering enzymes aimed at the efficient conversion of single-carbon feedstocks. Responsibilities include:
- Performing biochemical characterization of naturally occurring enzymes.
- Improving enzyme properties via diverse approaches, including:
- Structure-based mutagenesis
- Growth-coupled selection
- Directed evolution.
- Collaborating with various partner institutions across Europe.
- Engaging in an innovative interdisciplinary research project.
How to Apply:
Interested candidates should submit the following documents:
- Motivation letter outlining relevant experience in enzyme characterization and engineering.
- Curriculum vitae.
- Contact details of 2-3 referees.
For inquiries about the position, please contact Dr. Lennart Schada von Borzyskowski at L.Schada.von.Borzyskowski@biology.leidenuniv.nl. For application procedure questions, contact Christina Kamerman at HR@biology.leidenuniv.nl.
Last Date for Apply:
5 February 2026
