Applications are invited for an exciting Postdoctoral Researcher position at the Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, University of Oxford. This role offers a unique opportunity to contribute to cutting-edge genome editing methods within the new MRC Centre of Research Excellence (CoRE) in Therapeutic Genomics, focusing on developing bespoke platforms for treating rare diseases.
Designation
- Postdoctoral Researcher
Research Area
- Genomics
- Genome Editing
- Therapeutic Genomics
- Rare Disease Treatment
Location
- Radcliffe Department of Medicine, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, UK
Eligibility/Qualifications
Essential:
- PhD (or submitted thesis) in Haematology, Genome Editing, or a related discipline.
- Relevant experience in the field.
- Experience conducting complex genome editing and single-cell genomics experiments.
- Experience designing and carrying out experiments with murine models of transplantation.
- Experience in purification of cells from blood and bone marrow using flow cytometry and cell sorting.
- Experience with advanced genome editing, including cloning of CRISPR gRNAs for custom screens, base editing (including alternative specificity Cas enzymes), and prime editing.
- Ability to work independently and as part of a team.
- Excellent communication skills.
Desirable:
- Experience with off-target assays such as CIRCLE-seq and GUIDE-seq.
- A strong publication record.
Job Description
The successful candidate will work with Professor James Davies and Professor Ronjon Chakraverty on a project focused on developing a bespoke platform for using genome editing to treat rare diseases. Key responsibilities include:
- Planning and executing laboratory research.
- Generating high-quality data.
- Writing up findings for publication in scientific journals.
- Presenting data and ideas at regular meetings.
- Regular reporting and communication with the Group Head.
Salary
Grade 7: £39,424 – £47,779 per annum
How to Apply
Applications for this vacancy must be made online. Applicants are required to upload a CV and a supporting statement as part of their online application.
Last Date to Apply
12:00 noon on 5 October 2026
