Summary
Utrecht University is inviting applications for a Postdoctoral position within the Chemical Biology and Drug Discovery division. This multidisciplinary project focuses on the discovery and development of novel Piezo1 inhibitors for sickle cell disease, utilizing a combination of virtual screening, AI-driven techniques, and organic synthesis.
Designation
Postdoctoral Researcher
Research Area
Medicinal Chemistry, Computational Drug Discovery, and Chemical Biology
Location
Utrecht University, Netherlands
Eligibility/Qualification
Candidates must meet the following requirements:
- A completed PhD in Medicinal Chemistry.
- Extensive experience in the organic synthesis of drug-like compounds.
- Practical experience in molecular modelling and docking for the creation of bioactive compounds.
- Strong proficiency in written and spoken English.
Job Description
The successful candidate will play a pivotal role in optimizing initial inhibitors and conducting broader screenings. Key responsibilities include:
- Combining fundamental research with translational potential to develop Piezo1 inhibitors.
- Collaborating closely with researchers at UMC Utrecht for compound assaying.
- Utilizing state-of-the-art synthetic labs, analytical equipment (NMR, LC/MS, MALDI-TOF), and large-scale computation facilities.
- Participating in periodic user committee meetings with experts in the field.
- Advancing successful compounds through subsequent translational activities.
How to Apply
Interested applicants should apply through the official university portal. Please prepare and enclose the following documents:
- A motivation letter.
- A comprehensive Curriculum Vitae.
- Names, telephone numbers, and email addresses of at least two professional references.
- A copy of your PhD certificate or an official letter confirming your defense date.
For more information regarding the position, you may contact prof dr. Roland J. Pieters at r.j.pieters@uu.nl.
Last Date for Apply
18 November 2026
Apply Link
Apply Now at Utrecht University
