Summary: The Tumor-Stroma Communication group is opening a postdoctoral position for a researcher interested in understanding how cancer cells interact with the surrounding stroma and how this crosstalk shapes tumor progression. The role centers on developing antibody-functionalized lipid nanoparticles to selectively block signaling pathways in specific tumor-associated cell types. The lab has a strong track record with publications in high-impact journals and offers an environment that blends basic biology, nanotechnology, and translational oncology.
Summary Table
| Field | Details |
|---|---|
| Designation | Postdoctoral Researcher |
| Research Area | Tumor–Stroma Communication, Cancer Biology, Nanoparticle Engineering |
| Location | Valencia, Spain |
| Experience Required | Must have less than 2 years of postdoctoral experience |
| Application Deadline | Not specified (apply as soon as possible) |
Designation
Postdoctoral Researcher – Tumor-Stroma Communication Laboratory
Research Area
The position focuses on cancer–stroma interactions, signaling pathways, endothelial biology, macrophage biology, and nanoparticle-based therapeutic strategies. The broader goal is to understand how cancer cells reshape their microenvironment and how this knowledge can drive new therapeutic approaches.
Location
Tumor-Stroma Communication Laboratory
Valencia, Spain
Eligibility / Qualification
- PhD in Biomedical Sciences, Biotechnology, Molecular Biology, Cancer Biology, Nanotechnology, or related fields.
- Less than two years of postdoctoral research experience.
- Strong background in cell biology, molecular biology, or cancer research is helpful.
- Experience with nanoparticles, in vivo models, or immunology is an advantage.
Job Description
You will work on a project developing functionalized lipid nanoparticles designed to inhibit specific signaling pathways in targeted cell populations within tumors. The work includes:
1. Nanoparticle Design and Validation
- Creating lipid nanoparticles conjugated with antibodies.
- Loading nanoparticles with pathway-specific inhibitors.
2. In Vitro Functional Studies
- Testing targeted pathway inhibition in endothelial and tumor cell lines.
3. In Vivo Cancer Models
- Working with mouse models of solid tumors and peritoneal carcinomatosis.
- Assessing therapeutic impact and toxicity.
4. Immune Profiling and Transcriptomics
- Performing flow cytometry-based tumor immunophenotyping.
- Conducting RNA-seq analyses to map pathway responses and microenvironmental changes.
How to Apply
Interested candidates should contact the lab directly for application details. Send your CV, a brief statement of research interests, and contact information for references to the provided email address mentioned in the original call.
Last Date to Apply
Until position filled
