Postdoctoral Researcher: T-B Immunological Synapse: The Institut Cochin is seeking a dedicated and skilled postdoctoral researcher to join our team in Paris to explore the mechanical communication mechanisms between immune cells, focusing on the interactions at the T-B immunological synapse.
Postdoctoral Researcher to Study the T-B Immunological Synapse
Designation
Postdoctoral Researcher (M/F)
Table
| Details | Information |
|---|---|
| Offer Title | Postdoctoral Researcher to study the T-B Immunological Synapse (M/F) |
| Reference | UMR8104-PAOPIE-004 |
| Number of Positions | 1 |
| Workplace | Paris 14 |
| Publication Date | 28 August 2025 |
| Contract Type | Researcher in FTC |
| Contract Duration | 24 months |
| Expected Start Date | 1 November 2025 |
| Work Proportion | Full Time |
| Remuneration | €3081 – €3401/month (gross) |
Research Area
Cellular Biology, Immunology, Biophysics
Location
Institut Cochin, Paris, France
Eligibility/Qualification
- Education: PhD in Biophysics, Cell Biology, Immunology, or related discipline.
- Technical Expertise: Proficiency in optical microscopy and quantitative image analysis.
- Engineering Skills: Knowledge of microfabrication, microfluidics, and mechanobiology.
- Interpersonal Skills: Ability to work in a multidisciplinary team with strong communication skills and scientific curiosity.
- Languages: Very good command of English; French is a plus but not required.
Job Description
The postdoctoral fellow will be engaged in an ANR-funded project aimed at investigating the physical processes by which B lymphocytes mechanically interact with T lymphocytes at the immunological synapse. Key responsibilities include:
- Studying mechanical crosstalk between B cells and T cells in immune synapse formation.
- Analyzing immune synapse structure and dynamics on substrates with varying mechanical/chemical properties.
- Employing microfluidics tools and pharmaceutical/genetic approaches to manipulate immune synapse formation.
- Measuring mechanical properties of cells using biophysical techniques.
- Learning group microfabrication methods (microfluidic traps, soft substrates).
- Utilizing techniques such as cell culture, microfluidics, and fluorescence microscopy.
How to Apply
Interested candidates should submit their application, including a CV and cover letter, through the provided portal on the Institut Cochin website.
Last Date for Apply
01 October 2025, 23:59 Paris time
