Postdoctoral Researchers: The Centre for Genomic Regulation (CRG) in Barcelona, Spain, invites applications for two postdoctoral positions in the Intracellular Compartmentation Lab. The successful candidates will contribute to an ERC-related project focusing on the expression of endoplasmic reticulum export site components at mitochondria, with a particular emphasis on understanding the mechanism of bulk cargo secretion in cells. The lab is dedicated to unraveling the intricate processes involved in the export of bulky cargoes, such as collagens, mucins, and chylomicrons, and aims to shed light on the underlying molecular and cellular mechanisms.
Designation: Postdoctoral Researchers
Research Area: Molecular Cell Biology, Imaging, Genetic Manipulation, Bulk Cargo Secretion, Endoplasmic Reticulum Export, TANGO1, Intracellular Compartmentation.
Location: Barcelona, Spain
Eligibility/Qualification:
Must Have:
- Comprehensive understanding and proven ability in modern molecular cell biology, imaging, and genetic manipulation.
- Fluent in English (written and spoken).
- Demonstrated expertise in relevant procedures, including genetic manipulation in metazoans, super resolution microscopy, and a track record of publications.
Desirable but not required/Nice to have:
- Expertise in imaging.
- Experience in protein purification.
- Interest in working with animal models.
- Familiarity with advanced bioinformatic tools (e.g., Python/R, omics data analysis).
Education and Training:
- PhD or no more than one year of postdoc.
- Demonstration of expertise through published papers in reputable journals.
Languages: Excellent scientific communication skills (demonstrated abilities in manuscript and grant writing, conference presentations, etc.).
Technical Skills: Modern approaches in molecular cell biology and superresolution microscopy.
Competences:
- Highly developed organizational skills.
- Ability to organize and conceptualize original ideas in science.
Job Description: The postdoctoral researchers will collaborate with the team in expressing endoplasmic reticulum export site components at mitochondria to recreate an ERES-related structure. They will investigate the mechanism by which cells secrete bulky cargoes, particularly collagens, mucins, and chylomicrons, exploring the role of transient tunnels and key components such as TANGO1. The role involves a mix of in vitro and in vivo analyses, utilizing optogenetically controlled functions and inhibitors to study both healthy and fibrotic tissues.
How to Apply: Interested candidates should submit the following documents through the CRG Career site (http://www.crg.eu/en/content/careers/job-opportunities):
- A motivation letter addressed to Dr. Vivek Malhotra.
- A complete CV, including contact details.
- Contact details of two referees.
Last Date for Apply: November 30, 2023
Selection Process:
- Pre-selection: Based on qualifications and expertise reflected in the candidates’ CVs.
- Interview: Preselected candidates will be interviewed by the Hiring Manager and a selection panel if required.
- Offer Letter: The successful candidate will receive a Job Offer from the People department, specifying the start day, salary, working conditions, among other important details.
Working Conditions:
- Contract duration: 3 years with the possibility of extension up to 5 years.
- Estimated annual gross salary: Commensurate with qualifications and consistent with CRG pay scales.
- Target start date: October/November 2023.
The CRG is committed to providing a diverse and inclusive environment, promoting work-life balance, and encouraging flexible working hours. The institute believes in ongoing improvement and welcomes candidate feedback to enhance the recruitment process.
Deadline: Please submit your application by 30 November 2023.
Suggestions: The CRG values continuous improvement and invites candidates to share suggestions or complaints regarding their recruitment experience through the provided feedback form. Your input is crucial in creating a positive candidate journey and contributing to ongoing enhancements in the recruitment processes.
