Postdoctoral Scientist – Chemical Biology: The Francis Crick Institute is looking for a dedicated Postdoctoral Project Research Scientist to join the Morreale Lab, focusing on developing innovative antibacterial strategies, including targeted protein degradation methods.
Postdoctoral Project Research Scientist – Chemical Biology & Antibacterial Drug Discovery
Designation
Postdoctoral Project Research Scientist
| Details | Information |
|---|---|
| Salary | From £45,500 with benefits, subject to skills and experience |
| Job Type | Full-time, fixed term (2 years) |
| Reports to | Francesca Ester Morreale, Group Leader |
| Research Area | Chemical Biology & Antibacterial Drug Discovery |
| Location | London |
Eligibility/Qualification
- Essential:
- PhD (or close to completion) in organic chemistry, medicinal chemistry, chemical biology, or a related discipline.
- Strong track record in synthetic organic chemistry, including route design and compound characterization.
- Solid understanding of medicinal chemistry concepts and drug discovery workflows.
- Desirable:
- Experience with biophysical techniques (e.g., SPR, ITC, DSF) and DNA-encoded library (DEL) screening.
- Experience in chemical biology and antibacterial drug discovery.
- Experience in collaborative consortium-based research environments.
Job Description
The successful candidate will:
- Lead their own project involving the design and synthesis of small molecules.
- Apply medicinal chemistry principles, emphasizing structure–activity relationship (SAR) analysis.
- Collaborate with microbiologists, biochemists, and structural biologists.
- Conduct biophysical characterization of protein-ligand interactions and/or DEL screening.
- Analyze data, maintain clear experimental records, and prepare manuscripts for publication.
- Contribute to a positive, inclusive lab environment and support junior researchers.
How to Apply
Applicants should submit:
- A cover letter outlining the motivation for joining the Morreale Lab.
- A CV including a publication list.
- Contact details for at least two academic referees.
Applications will be reviewed on a rolling basis until the position is filled.
Last Date to Apply
Until position filled
For further details and to apply, please visit the Francis Crick Institute’s careers webpage.
