Research Associate at Cambridge : The Department of Medicine invites applications for a talented and enthusiastic post-doctoral scientist to join Prof Paul J Lehner FRS’s group on a Wellcome Trust funded project. The project focuses on elucidating the mechanisms of the HUSH epigenetic transcriptional silencing complex and its role in genome immunosurveillance, with implications for therapeutic development. The successful candidate will employ molecular, biochemical, and cell biological techniques, along with CRISPR/Cas9 tools and bioinformatic analyses, to investigate HUSH activity. This position offers an exceptional opportunity to work in the Cambridge Institute of Therapeutic Immunology and Infectious Disease (CITIID) within a collaborative and interdisciplinary research environment.
| Designation | Research Area | Location |
|---|---|---|
| Research Associate | Chromatin Biology, Epigenetics, RNA Biology | Cambridge Institute of Therapeutic Immunology and Infectious Disease, Cambridge Biomedical Campus |
Eligibility/Qualification:
- PhD in molecular biology, biochemistry, or a related discipline.
- Background in chromatin biology, epigenetics, or RNA biology.
- Expertise in CRISPR/Cas9-mediated genome engineering and/or genomics techniques is desirable.
- Strong initiative, creativity, and time management skills.
- Experience in retroelement biology or iPSC work is beneficial.
Job Description:
- Investigate the mechanisms of the HUSH epigenetic transcriptional silencing complex.
- Employ molecular, biochemical, and cell biological techniques to study HUSH activity.
- Utilize CRISPR/Cas9 tools and bioinformatic analyses for data interpretation.
- Collaborate with colleagues in different disciplines within the lab.
- Contribute original insights and manage research priorities effectively.
How to Apply: To apply, click the ‘Apply’ button below and register an account with our recruitment system. Upload a covering letter outlining your suitability for the role and a CV in the Upload section. Ensure to include details of referees, including email address and phone number.
Last Date for Apply: 9 April 2024
Contact:
- Prof Paul J Lehner: pjl30@cam.ac.uk
- Website: Lehner Lab
Additional Information:
- Appointment at Research Associate level requires a PhD or an equivalent research doctorate. Candidates who have submitted but not yet received their PhD will be appointed at Research Assistant level.
- The position is fixed-term for 3 years in the first instance.
- The University actively supports equality, diversity, and inclusion.
- Applicants must be eligible to live and work in the UK.
Department/Location: Department of Medicine, Cambridge Biomedical Campus
Salary: £36,024-£44,263
Reference: RC40951
Published: 19 March 2024
Closing Date: 9 April 2024
