Imperial College London is seeking a dedicated and innovative Research Associate to join Dr. Szymon W. Manka’s research group. This full-time, fixed-term position focuses on investigating the molecular pathways of prion pathogenicity, contributing to our understanding of neurodegeneration through the application of cutting-edge structural and cell biology techniques.
Designation
Research Associate
Table
| Details | Information |
|---|---|
| Job Number | MED05141 |
| Salary Range | £48,056 – £56,345 per annum |
| Contract Type | Full-time, Fixed-term (24 months) |
| Location | South Kensington Campus, Imperial College London |
| Posting End Date | 21 March 2025 |
Research Area
- Molecular pathways of prion pathogenicity
- Neurodegenerative diseases, including Alzheimer’s and Parkinson’s diseases
Location
South Kensington Campus, Imperial College London (On-site only)
Eligibility/Qualification
- PhD degree or equivalent in a relevant field
- Proven track record of conducting original and high-quality research
- Desirable: Knowledge and research experience in using cryo-electron microscopy (cryo-EM) for high-resolution structure determination
Candidates who have not yet received their PhD will be considered for a Research Assistant position, with a salary range of £43,003 – £46,297 per annum.
Job Description
The successful candidate will:
- Investigate the sites and molecular determinants of prion propagation in cellular and tissue contexts.
- Identify prion interaction partners that may serve as pathogenicity mediators, informing future development of anti-prion therapeutics.
- Collaborate with the Electron Bio-Imaging Centre (eBIC) at Diamond Light Source Ltd, involving advanced cryo-EM facilities.
- Utilize cutting-edge techniques such as cryo-correlated light and electron microscopy/tomography (cryo-CLEM/ET).
Responsibilities:
- Engage in high-quality research to pinpoint sites of prion propagation.
- Collaborate with interdisciplinary teams to advance understanding of prion diseases.
- Contribute to grant applications and seek opportunities for future research funding.
How to Apply
Interested candidates should complete the application process through the Imperial College London job portal. For further information or informal inquiries, please contact Dr. Manka directly at smanka@ic.ac.uk.
Last Date to Apply
21 March 2025
Imperial College London is committed to equality, diversity, and inclusion. We encourage applications from all backgrounds and communities.
