Research Associate in Circadian Biology: The Brancaccio Lab at Imperial College London’s Department of Brain Sciences is seeking a highly motivated and creative postdoctoral researcher to lead projects investigating molecular mechanisms driving circadian dysfunction in pre-clinical models of Alzheimer’s disease.
Designation
Research Associate in Circadian Biology
| Detail | Information |
|---|---|
| Job Number | MED05021 |
| Salary Range | £48,056 – £56,345 per annum |
| Contract Type | Fixed term |
| Work Pattern | Full time |
| Location | Hammersmith Campus – Hybrid |
| Posting End Date | 3 April 2025 |
Research Area
Circadian Biology and Neurodegenerative Disorders
Eligibility/Qualification
- A PhD in neuroscience or a related field (or near completion).
- Experience with laboratory techniques including live imaging microscopy and advanced molecular biology.
- Proficiency in software packages such as MATLAB, ImageJ, SigmaPlot, Prism, or R, along with experience in statistical analysis.
- Practical experience with RNAseq, RNA scope, and spatial transcriptomic techniques is highly desirable.
- Knowledge of multivariate statistical analysis of (circadian) time series is highly beneficial.
Job Description
You will develop new molecular tools modifying circadian pathways to prevent/delay Alzheimer’s disease. Responsibilities include:
- Performing viral delivery of gene therapy viral vectors.
- Conducting behavioral assessments of sleep-wake cycles and cognition.
- Engaging in multiplexed live imaging of brain tissue.
- Utilizing combinatorial intersectional genetics and multivariate statistical analysis of time series for validating new chronotherapeutic interventions.
- Previous knowledge of circadian biology is desirable but not mandatory.
How to Apply
Interested candidates should apply through the Imperial College London job portal. For inquiries, you may contact Dr. Marco Brancaccio at m.brancaccio@imperial.ac.uk.
Last Date for Apply
Please apply as early as possible as the posting may close prior to the specified end date if a high volume of applications is received. The official closing date is 3 April 2025.
Join us in our mission to deliver transformative breakthroughs in therapies for neurodegenerative disorders and help shape the future of science for humanity!
