Two Postdoctoral Positions:: Join the lab of James Gahan at the Centre for Chromosome Biology, University of Galway, Ireland, and contribute to cutting-edge research on the role of chromatin during cell differentiation in choanoflagellates. These positions are funded by an ERC Starting Grant and the Wellcome Trust, and the lab opens in April 2024. Explore the mechanisms driving life history transitions in choanoflagellates using omics approaches, microscopy, transgenesis, and genome-editing tools.
Designation: Postdoctoral Researcher
Research Area: Understanding Chromatin’s Role in Cell Differentiation in Choanoflagellates
Location: Centre for Chromosome Biology, University of Galway, Ireland
Eligibility/Qualification:
- Ph.D. in molecular biology, biochemistry, or a related discipline.
- Proven track record in research, including 1st author publications.
- Experience in bioinformatics (Position 1) or genome editing (Position 2) is advantageous.
- Knowledge of evolutionary or chromatin biology is a plus.
- Highly motivated and research-driven.
Job Description:
Two Postdoctoral Positions: Understanding Chromatin’s Role in Cell Differentiation in Choanoflagellates
In this exciting opportunity, you will be part of a new lab with a focus on understanding how changes in genome regulation contributed to animal evolution. The lab’s research involves:
Position 1: Dissecting Transcriptional and Epigenetic Changes
- Use multiple -omics technologies (ChIPseq, ATACseq, MicroC, etc.) to define transcriptional and epigenetic changes during cell differentiation in S. rosetta cells.
- Lead efforts to unravel the mechanisms underlying differentiation in choanoflagellates.
Position 2: Investigating Polycomb-Mediated Repression
- Explore the role of Polycomb-mediated repression in S. rosetta.
- Generate transgenic and mutant tools using CRISPR-Cas9.
- Dissect the function and targeting mechanism of Polycomb in S. rosette.
Both positions offer the opportunity to work on cutting-edge research projects with a strong emphasis on understanding chromatin’s role in cell differentiation.
What we offer:
- Flexible start dates after May 1, 2024.
- Competitive starting salary of €42,033 (gross).
- Funding for 4 years (Position 1) or 3 years (Position 2), with potential for extension depending on funding.
- A vibrant research environment at the Centre for Chromosome Biology.
How to Apply: Interested candidates should submit the following documents to James Gahan (james.gahan@bioch.ox.ac.uk):
- CV
- Cover letter explaining your research/career goals and motivation for applying.
- Contact details of two referees.
Last Date for Apply: The positions will remain open until filled.
Join us in unraveling the mysteries of genome regulation and chromatin’s role in cell differentiation. Be part of a new lab at the forefront of choanoflagellate research and contribute to groundbreaking discoveries in the field of evolutionary biology.
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