Designation/Position- 2-Year Post-Doctoral Position
VIMM Institute of Padova, Italy, invites applications for 2-Year Post-Doctoral Position from eligible and interested candidates
About- Since mutations in the GJB1 gene that encodes connexin 32 (Cx32) were first reported in 1993, more than 450 different mutations associated with the X-linked form of Charcot–Marie–Tooth disease (CMT1X) have been discovered. A path from genetic diagnosis to personalized treatment is still unavailable, as the molecular mechanisms underlying the disease remain unclear. A new paradigm for the molecular pathogenesis of CMT1X has recently been suggested to be no longer related to Cx32 paired gap junction channels, but rather to unpaired channels (hemichannels), which could mediate ATP-induced ATP release signaling regulating Schwann cell myelination. The objectives of this basic science project are: (i) to provide evidence that Cx32 hemichannel dysfunction underlies CMT1X pathogenesis; (ii) to develop in vitro assays that can be utilized to test candidate therapeutic compounds that will benefit patients affected by different CMT1X mutations.
Research/Job Area- Life Sciences/Biophysics
Location- VIMM Institute of Padova, Italy
Eligibility/Qualification–
- Applications are solicited from candidates holding a master’s degree (or equivalent degree), with at least three years of research experience, or a Ph.D.
- A scientific biophysical background involving fluorescence microscopy and electrophysiology is required. Candidates will also be evaluated based on motivation, flexibility and proven ability to work independently.
Job/Position Description-
2-year post-doctoral position in the field of Connexins and peripheral neuropathies
at VIMM Institute of Padova, Italy
Research group is looking for a highly motivated candidate for a project titled: “Linking Cx32 hemichannel dysfunction to Charcot-Marie-Tooth pathogenesis”
Supervisor: Prof. Mario Bortolozzi, Department of Physics and Astronomy “G. Galilei”, University of Padua, (Padova), Italy (http://www.vimm.it/scientific-board/mario-bortolozzi/).
Employer: University of Padua. Website: http://www.unipd.it/en/.
Job salary: 30,000 euro/year (gross amount).
Job hours: Full-time.
How to Apply-
To apply for this position, candidates should send an email to mario.bortolozzi@unipd.it, including:
1) a cover letter describing the scientific experience, interests, and career goals;
2) full CV;
3) the names and contact information of at least two professional references.
Applications will be reviewed immediately and considered until the position is filled.
Last Date for Apply– Until the position filled
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