PhD Thesis Project Scholarship: The Institut Curie Research Center, in collaboration with 4Dcell and the Paris Cardiovascular Research Center, is offering a PhD thesis project scholarship focusing on the study of myocardial ageing. This interdisciplinary project aims to uncover the biological mechanisms involved in heart ageing and explore potential interventions to improve cardiovascular health in the elderly.
PhD Thesis Project Scholarship at Institut Curie Research Center
Designation
PhD Thesis Project (H/F)
Research Area
- Cellular and Molecular Biology
- Computational Biology
- Ageing of the Heart
- Artificial Intelligence
Location
- Institut Curie, Paris
- 4Dcell, Montreuil (93100)
Eligibility/Qualification
- Master’s degree in Cellular or Molecular Biology and/or Computational Biology.
- Experience in a research laboratory focused on molecular or cellular biology.
- Preferred experience with cardiomyocyte culture maintenance and differentiation of iPSCs (cell types: cardiomyocytes, fibroblasts, endothelial cells, etc.).
- Skills in programming (R, Python, and/or Matlab) and data processing.
- Problem-solving mindset.
- Motivation for wet-lab experimentation.
- Ability to work effectively in a team.
- Excellent communication skills in English.
Job Description
The PhD student will be part of the INSERM U932 “Immunity and Cancer” research unit at the Institut Curie. The project involves:
- Studying the cellular and molecular ageing of the SmartHeart cardiac organoid.
- Building a non-destructive biological clock for the SmartHeart.
- Modelling the experimental data and behaviour of the SmartHeart to generate a digital twin.
- Testing pharmacological interventions that impact the biological ageing of the SmartHeart.
The student will spend 70% of their time at 4Dcell in Montreuil under the co-direction of Dr. Christophe Pannetier.
How to Apply
Interested candidates should send their CV, a letter of motivation, and contact information for two references (name, phone, email, and description of the relationship with the candidate) to the provided contact.
Last Date to Apply
Applications will be accepted until September 30, 2024, or until the position is filled.
For more information and to apply, visit the Institut Curie Research Center.
