Postdoctoral Scientist in Cell Biology: The University of Würzburg is seeking a motivated postdoctoral scientist to join our research team as part of the European Research Council Advanced Grant Tryplaxis. The position is available for 2 years starting from November 1, 2024. The successful candidate will investigate cAMP signaling in Trypanosoma brucei, focusing on its role in tissue and organ tropism within mammalian hosts.
Postdoctoral Scientist in Cell Biology and Molecular Parasitology
Designation:
Postdoctoral Scientist
Research Area:
Cell Biology, Molecular Parasitology
Location:
University of Würzburg, Würzburg, Germany
Eligibility/Qualification:
- Strong background in molecular and cell biology
- High degree of organization and rigor
- Prior experience in or willingness to learn bioinformatics
- Ability to work both independently and as part of a team
- Motivation and curiosity to think outside the box
- Record of peer-reviewed publications
- Previous experience in genetic manipulation of trypanosomes is an advantage
Job Description:
The project aims to explore how the unicellular parasite Trypanosoma brucei, which causes trypanosomiasis in sub-Saharan Africa, senses and reacts to its environment. The focus will be on producing a barcoded library of approximately one hundred gene deletions using CRISPR/Cas9 technology. These mutants will be tested in mouse infection experiments, and selected knockouts with strong phenotypes will be further analyzed by intravital microscopy. Responsibilities include:
- Conducting advanced molecular and cell biology experiments
- Producing and validating gene deletions in Trypanosoma brucei
- Analyzing data and interpreting results
- Collaborating with an international team of scientists
- Presenting research findings at national and international conferences
We Offer:
- State-of-the-art laboratories and equipment
- Technical support for cell culture and knockout validation
- Opportunities for training in bioinformatics
- Interactions with an international network of scientists
- Opportunities to present your work at national and international conferences
- Collaborative animal experiments conducted in Portugal and the US following 3R principles
How to Apply:
Interested candidates should send their application, including a CV, copies of degrees, a summary of previous research experience and research interests, and the names of two referees, to Prof. Isabel Roditi at isabel.roditi@unibe.ch. Informal inquiries are welcome.
Last Date for Apply:
Please submit your application by October 15, 2024.
