PhD Position on Human Cells: The International PhD Programme (IPP) in Mainz is offering a fully funded PhD position focused on understanding the role of R-loops in genomic instability, under the supervision of Dr. Petra Beli. This project is part of the DFG-funded SFB 1361 program, inviting applications from ambitious students ready to engage in cutting-edge research in the Life Sciences.
PhD Position on R-Loops as Drivers of Genomic Instability in Human Cells
Designation
PhD Position: R-loops as Drivers of Genomic Instability in Human Cells (M/F/D)
| Category | Details |
|---|---|
| Research Area | Molecular Biology, Genome Stability |
| Location | Mainz, Germany |
| Application Deadline | 16 October 2025 |
| Starting Date | 1 February 2026 |
| Duration | 3 years |
| Funding | Fully funded position |
| Working Language | English |
| Required Degree | Master or equivalent |
Eligibility/Qualification
- A Master’s degree or equivalent in a relevant field.
- Strong command of the English language.
- An interactive personality and the ability to collaborate across disciplines.
- Two letters of reference.
Description
The PhD project investigates R-loops, which are RNA-DNA hybrids formed during transcription. These structures can lead to genomic instability when accumulated, causing issues such as DNA double-strand breaks. The successful candidate will utilize quantitative proteomics to explore how Ribonuclease H1 regulates R-loop resolution and analyze the interplay between R-loop accumulation and inflammatory responses. The project promises collaboration with a vibrant community of scientists and access to state-of-the-art facilities and training.
How to Apply
Interested candidates should apply via the IPP application platform, specifying Dr. Petra Beli’s group as their preference. Required documents include:
- Motivation letter
- Curriculum Vitae (CV)
- Academic certificates
- Transcripts
- References
For further details and to complete your application, please visit: International PhD Programme Mainz.
Last Date to Apply
16 October 2025
Interviews for shortlisted candidates will take place on 19 & 20 January 2026.
