Postdoctoral Researcher in Synthetic Biology – University Pompeu Fabra, Barcelona, Spain

Postdoc in Spain

Postdoctoral Researcher in Synthetic Biology: The Synthetic Cell Programming Lab led by Dr. Javier Santos-Moreno at the University Pompeu Fabra (UPF), Barcelona, invites applications for a Postdoctoral Researcher position. The successful candidate will design and engineer synthetic gene circuits to program temporal tasks in E. coli cells as part of the ERC Starting Grant project “TICK-TOCK Do and Die.”

This is an exciting opportunity to join a young, dynamic, and international research group located at the Biomedical Research Park of Barcelona (PRBB) — one of Europe’s leading life sciences hubs.


📋 Position Summary Table

FieldDetails
DesignationPostdoctoral Researcher (Postdoc)
Research AreaSynthetic Biology, Genetic Circuit Engineering
Project TitleTICK-TOCK Do and Die (ERC Starting Grant)
Principal InvestigatorDr. Javier Santos-Moreno
InstitutionUniversity Pompeu Fabra (UPF)
DepartmentMedicine and Life Sciences (MELIS)
LocationBiomedical Research Park of Barcelona (PRBB), Spain
Contract DurationUp to 3.5 years (Full-time)
Start Date1st January 2026 or upon agreement
Application Deadline26th October 2025 or until filled

🧫 Designation

Postdoctoral Researcher – Synthetic Biology


🔍 Research Area

Synthetic Biology, Gene Circuit Design, CRISPRi Systems, Temporal Programming in E. coli.


📍 Location

Synthetic Cell Programming Lab,
Department of Medicine and Life Sciences (MELIS),
University Pompeu Fabra (UPF),
Biomedical Research Park of Barcelona (PRBB), Spain


🎓 Eligibility / Qualification

Required:

  • Ph.D. in Life Sciences or related field.
  • One or more first-author publications in major peer-reviewed international journals.
  • Strong background in wet-lab synthetic or molecular biology.

Highly Desirable:

  • Experience in gene circuit design or computational modeling.

Desirable:

  • Experience in one or more of the following:
    • NGS sequencing (Illumina, Nanopore, etc.)
    • Base editing, synthetic memory, biocontainment, bioproduction, or microfluidics.

Skills & Competencies:

  • High motivation, scientific rigor, and integrity.
  • Strong organizational and teamwork skills.
  • Proficient in written and spoken English.
  • Ability to work independently in a collaborative environment.

🧪 Job Description

The postdoctoral researcher will:

  • Design and build synthetic gene circuits to program temporal behaviors in E. coli.
  • Use CRISPRi, transcription factors, and molecular cloning tools to construct and fine-tune circuits.
  • Characterize systems using microplate readers, flow cytometry, and fluorescence microscopy.
  • Collaborate on circuit integration and optimization with other group members.
  • Publish research articles and present findings at scientific conferences.
  • Mentor PhD and undergraduate students and participate in collaborative projects.
  • Optional: engage in teaching and outreach activities.

💼 What We Offer

  • Full-time postdoctoral contract (up to 3.5 years).
  • Competitive salary and full benefits under the Spanish social security system.
  • 36 paid holidays per year (22 personal + 14 bank holidays).
  • Access to public healthcare, retirement, and unemployment benefits.
  • Flexible work policies, including parental leave and family-life balance support.
  • Access to career development programs, free training courses, and mentoring.
  • Collaborative, international, and inclusive research environment within the PRBB community.

📨 How to Apply

Send a single PDF titled
Postdoc-timers-Nov_yourName_yourSurname.pdf
to javier.santos@upf.edu with the subject line:
“Postdoc timers 2025”

The PDF should include:

  1. Motivation Letter
  2. Curriculum Vitae (with publication list)
  3. Contact details of three references

Include your ID/Passport number in the body of the email.


📅 Last Date to Apply

26th October 2025 (or until the position is filled)


📧 Contact for Queries

Dr. Javier Santos-Moreno
Email: javier.santos@upf.edu
Lab Website: santosmorenolab.org

Link

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