PhD in CRISPR–Cas-Based Biosensors: ETH Zurich is seeking a motivated PhD student to develop innovative CRISPR-Cas-based electrochemical biosensors aimed at addressing multidrug-resistant Mycobacterium tuberculosis (MDR-MTB). This project, funded by an SNSF BRIDGE Discovery grant, supports cutting-edge research that could transform TB diagnosis and treatment in low- and middle-income countries.
PhD Scholarship Opportunity in CRISPR–Cas-Based Electrochemical Biosensors
Designation
PhD Student in In Vitro Diagnostics, CRISPR–Cas / Electrochemistry
Research Area
- CRISPR-Cas Technology
- Electrochemical Biosensing
- Tuberculosis (TB) Diagnostics
- Global Health
Location
ETH Zurich, Switzerland & Swiss Center for Electronics and Microtechnology (CSEM)
Eligibility/Qualification
- Master’s degree in a relevant science or engineering discipline
- Background in CRISPR-Cas and/or electrochemical biosensing preferred
- Experience in biosensing or analytical chemistry will also be considered
- Passionate about science, engineering, and global health
Description
The PhD project focuses on the development of RPA–CRISPR–Cas assays for multiplexing 14 TB targets and associated drug resistance markers from single samples. It aims to create low-cost diagnostic technologies that can be used at the point-of-care (PoC), especially in low-resource settings. The selected candidate will work collaboratively within a multi-institutional consortium and will be involved in both laboratory research and fieldwork in Georgia.
How to Apply
Interested candidates are invited to submit their applications online, including:
- A cover letter detailing motivation and meeting the position requirements
- A detailed CV
- Contact information for at least two references
Last Date to Apply
Applications will be assessed continuously, with a shortlist for interviews drawn up by mid-February. The anticipated start date for the selected candidate is in 2026.
For any questions regarding the position, please contact Dr. Daniel Richards at daniel.richards@chem.ethz.ch or Dr. Loïc Burr at loic.burr@csem.ch.
This scholarship offers a unique opportunity to contribute to a vital area of public health, facilitating improved TB diagnosis and treatment, particularly in resource-limited settings.
