Summary: The University of Leicester is seeking a highly motivated Post-Doctoral Research Associate for a BBSRC-funded project focused on the molecular grammar of cell-type specific alternative splicing regulation. This role offers an exciting opportunity to work at the intersection of molecular and cell biology in a collaborative environment.
Designation
Post Doctoral Research Associate
| Details | |
|---|---|
| Vacancy ID | 12926 |
| Salary | Grade 7 – ยฃ39,906 to ยฃ46,049 per annum, pro-rata if part-time |
| Hours per Week | 37.5 |
| Vacancy Terms | Full-time, or job share considered, fixed term contract for 12 months |
| Advert Closes | Midnight on 04 Mar 2026 |
Research Area
Molecular and Cell Biology
Location
Leicester, United Kingdom
Eligibility/Qualification
- A high-quality first degree and PhD in Biochemistry or a related subject (or near completion).
- Strong track record of research; demonstrated through publications and presentations.
- Hands-on experience in single-molecule microscopy.
- Skills in optics or photonics.
- Proven ability in developing software for imaging analysis, particularly using Python.
Job Description
The successful candidate will conduct research on the regulation of smooth muscle cell-specific splicing, utilizing advanced biophysical, structural, molecular, and chemical biology techniques. The role entails:
- Designing and building a TIRF microscope with annular excitation pathways.
- Creating a user interface for this microscope.
- Conducting single molecule TIRF microscopy.
- Analyzing RNA-protein interactions using techniques such as FRET.
Collaboration with an interdisciplinary team at the University of Cambridge and University of Leicester is a key component of this role.
How to Apply
Interested applicants should submit their CV and a cover letter detailing their interest and qualifications. Informal enquiries can be directed to Professor Ian Eperon at eci@leicester.ac.uk.
Last Date for Application
Midnight on 04 March 2026
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