PhD / Postdoctoral Position (Ribo-PAUSE Project): We invite applications for a PhD or Postdoctoral Researcher position focused on translational regulation in bacteria, particularly ribosome pausing and cold adaptation mechanisms. The project investigates gene expression regulation at the translational level in Bacillus subtilis, Myxococcus xanthus, and psychrophilic Antarctic bacterial strains using advanced molecular and imaging techniques.
The position is available under the NCN SONATA project “Ribo-PAUSE”, aiming to uncover new regulatory layers of bacterial translation and sporulation.
PhD / Postdoctoral Position in Bacterial Translation Regulation and Ribosome Biology (Ribo-PAUSE Project)
Summary Table
| Item | Details |
|---|---|
| Position | PhD Student / Postdoctoral Researcher |
| Project Title | Translation Regulation in Bacteria (NCN SONATA: Ribo-PAUSE) |
| Research Focus | Ribosome pausing, translational control, cold adaptation |
| Start Date | October 1, 2026 |
| Employment Period | April/May 2026 – October 2028 |
| Techniques Used | NGS (Ribosome Profiling), Confocal Microscopy, Polysome Profiling, In Vitro Translation, Mass Spectrometry |
| Application Contact | olgaiwanska@ibb.waw.pl, agatastarosta@ibb.waw.pl |
Designation
- PhD Candidate (Biology / Biotechnology / Biochemistry)
or - Postdoctoral Researcher (depending on qualifications)
Research Area
- Molecular Biology
- Microbiology
- Translational Regulation
- Ribosome Biology
- Cold Adaptation Mechanisms
- Functional Genomics
The research involves bacterial models including Bacillus subtilis, Myxococcus xanthus, and psychrophilic Antarctic bacteria.
Location
Institute of Biochemistry and Biophysics, Polish Academy of Sciences (IBB PAS), Poland.
Eligibility / Qualification
Essential Requirements
- PhD (for Postdoc) or MSc (for PhD position) in Biology, Biotechnology, Biochemistry, or a related field
- Experience in:
- Protein biosynthesis studies
- Working with bacterial systems
- Nucleic acid isolation and molecular biology techniques
- Strong background in genetics and microbiology
- Proficiency in English (written and spoken)
Desirable Skills
- Experience with:
- Next Generation Sequencing (NGS), especially ribosome profiling
- Polysome profiling
- In vitro translation assays
- Mass spectrometry
- Confocal or fluorescence microscopy
- Cryo-electron microscopy (optional)
- Experience with isolation and handling of Antarctic or psychrophilic bacteria
Job Description
The selected candidate will:
- Investigate ribosomal pausing and its role in translational regulation
- Study how translation of mRNAs is modulated by ribosomes and associated translation factors
- Analyze how ribosome pausing affects sporulation regulation in Bacillus subtilis
- Contribute to building the first comprehensive picture of cold-adapted translation machinery in Antarctic bacteria
- Characterize:
- Translation machinery
- Transcriptome and translatome
- In vitro translation apparatus
Methodologies Used
- Next Generation Sequencing (including ribosome profiling)
- Confocal and fluorescence microscopy
- Polysome profiling
- In vitro translation assays
- Mass spectrometry
- Cryo-electron microscopy (optional)
The project integrates cutting-edge molecular biology and imaging approaches to uncover a novel regulatory layer of translation in bacteria.
How to Apply
Interested candidates should send:
- CV (including publication list, if applicable)
- Motivation letter
- Contact details of references
📧 Applications and inquiries should be sent to:
Please include “Ribo-PAUSE Application” in the subject line.
Last Date to Apply
Applications are open until the position is filled. Early application is strongly encouraged.
