Summary
The Karolinska Institutet is offering a doctoral (PhD) student position focused on post-translational gene regulation within hematopoiesis. The research aims to understand the molecular, cellular, and immune pathways involved in malignant hematopoiesis, particularly in myeloid neoplasms.
Doctoral Scholarship in Post-Translational Gene Regulation in Hematopoiesis, Sweden
Designation
PhD Placement
| Detail | Information |
|---|---|
| Research Area | Post-Translational Gene Regulation |
| Location | Flemingsberg campus, Stockholms län, Sweden |
| Eligibility/Qualification | Master’s degree in biomedicine, molecular biology, cell biology, or bioinformatics |
| Application Deadline | April 20, 2026 |
Research Area
The Pedro Moura team is investigating:
- Expansion efficiency of mutant hematopoietic stem cells (HSC) vs. healthy HSC
- Restoration of production or function of differentiated myeloid lineage cells
- Immune system’s failure to clear mutant cells
Eligibility/Qualification
General Requirements
- Master’s qualification (second-cycle/advanced).
- 240 credits with at least 60 at advanced level.
- Equivalent knowledge from international institutions.
Specific Requirements
- Proficiency in English: Equivalent to English B/English 6 at Swedish upper secondary school.
Description
The doctoral project will focus on the role of post-transcriptional gene regulation (PTGR) mechanisms in malignancy and hematopoiesis. The candidate will engage in mechanistic studies using advanced gene editing technologies and high-throughput omics methodologies to investigate the pathogenesis of myeloid neoplasms.
Skills and Personal Qualities
Required:
- Strong academic background in relevant disciplines.
- Hands-on experience with gene editing (CRISPR-Cas9, siRNA), flow cytometry, and high-throughput omics.
Desirable:
- Experience in bioinformatics and programming (R, Python).
How to Apply
Applications should be submitted through the Varbi recruitment system. Required documents include:
- Personal letter
- Curriculum vitae
- Documentation of degree projects
- Certificates confirming eligibility
Last Date to Apply
April 20, 2026
For more information or to apply, contact:
- Pedro Moura: pedro.moura@ki.se
- Anna Heinerö: anna.heinero@ki.se
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