Summary
The UT Southwestern Medical Center is seeking a highly motivated Postdoctoral Researcher to lead efforts in characterizing protein-small molecule interactions and their functional consequences in cellular systems. This role focuses on advanced techniques in protein expression, purification, and analytical methods.
Postdoctoral Researcher in Protein-Small Molecule Interactions, UT Southwestern Medical Center, Dallas, Texas
Designation
Postdoctoral Researcher
Location
Dallas, Texas
Eligibility/Qualification
- Degree: Ph.D. in Chemistry, Biochemistry, Biophysics, Biology, or a related discipline.
- Strong background in molecular and cellular biology techniques.
Job Description
The successful candidate will be responsible for:
- Expression and purification of recombinant proteins.
- Conducting quantitative analysis of ligand binding via isothermal titration calorimetry (ITC).
- Evaluating target engagement in live cells using NanoBRET-based assays.
- Assessing protein levels and degradation through Western blotting and luminescence-based methods, including the HiBiT system (Promega).
How to Apply
Interested applicants should email the Principal Investigator (PI) at uttam.tambar@utsouthwestern.edu with the following documents:
- CV (including publications and contact details for 3 references)
- One-page cover letter summarizing:
- Past research experiences and accomplishments
- Potential research questions of interest in the Tambar Lab and why you fit well
- Goals for your postdoctoral training
- Long-term career goals and ideal timeframe for next steps
- Potential start date
Last Date to Apply
Until position filled
This position promotes equal opportunity, and applications from all qualified candidates are encouraged, regardless of race, color, religion, national origin, sex, sexual orientation, gender identity, age, disability, or veteran status.
