Summary
The Singapore-ETH Centre, in collaboration with ETH Zurich, is offering a fully funded PhD position focused on advanced patient-derived 3D Bone Organoids for in vitro osteoporosis research. This project aims to enhance understanding of osteoporosis mechanisms and develop personalized strategies for fracture prevention.
Designation
PhD Researcher – Bone Organoids
| Details |
|---|
| Research Area: Biomedical Engineering, Bone Organoids, Osteoporosis Research |
| Location: Singapore-ETH Centre, Singapore |
| Duration: Fixed-term |
Research Area
The research will involve developing patient-derived organoids for in vitro osteoporosis research, integrating biomedical, engineering, and computational approaches to study bone remodelling and immune interactions.
Eligibility/Qualification
- Degree: MSc in Biomedical Engineering or a related discipline.
- Experience: Prior experience in tissue engineering, mammalian cell culture, and familiarity with 3D cell culture, organoids, and bone or musculoskeletal research.
- Tech Skills: Proficiency in molecular, histological, and imaging techniques, as well as potential familiarity with data analysis tools such as Python.
- Language: Proficient in written and spoken English.
- Personal Qualities: Highly motivated, resilient, and capable of addressing experimental challenges in a collaborative environment.
Job Description
- Develop patient-derived organoids for in vitro osteoporosis research.
- Integrate peripheral blood mononuclear cells to model immune-bone interactions.
- Investigate donor-specific differences in bone remodelling and mineralization dynamics.
- Characterize osteoporosis-related organoid phenotypes using various techniques.
- Collaborate with engineers, clinicians, and biologists to generate comprehensive biological datasets for personalized bone health modeling.
How to Apply
Interested candidates should submit their applications online, including:
- A cover letter detailing motivation for the project.
- A CV with contact information for two academic references.
- University transcripts in PDF format.
Note: Applications via email or postal services will not be considered.
Last Date to Apply
Open Now
Please check the official website for application deadlines. Specific dates may be subject to change, so early application is advisable.
For more information, visit the Singapore-ETH Centre website or contact Prof. Dr. Ralph Müller at ram@ethz.ch.
