Postdoctoral Research Associate – Department of Paediatrics, University of Oxford, UK

Summary:

The Department of Paediatrics at the University of Oxford is seeking a motivated and highly organized Postdoctoral Researcher to contribute to a new and ambitious research program focused on developing innovative genetic therapies for rare genetic diseases. This is a unique opportunity to play a core role in a multidisciplinary team, contribute to strategic direction, and engage with leading national and international initiatives in the field of rare disease therapeutics.

Postdoctoral Research Associate – Department of Paediatrics, University of Oxford, UK

Designation: Postdoctoral Research Associate

Research Area:

• Developing novel therapeutic strategies for rare genetic disorders
• Developing computational tools for target identification and prioritization
• Standardizing therapeutic actionability assessments and translating them into practical resources for clinicians and patients

Location: Institute of Developmental & Regenerative Medicine (IDRM), Old Road Campus, Oxford

Eligibility/Qualification:

• PhD/DPhil (or near completion) in a biomedical science field, preferably with experience in Neuroscience/Genetics.
• Proven experience in mammalian cell culture and molecular biology.
• Highly effective verbal and written communication skills.
• Ability to operate effectively in a demanding and interdisciplinary research environment.

Job Description:

The successful candidate will lead an independent research project focused on expanding the possibilities of mRNA modulation through novel exon skipping strategies using antisense oligonucleotides. This role involves contributing to a translational and multidisciplinary research program led by Dr. Marlen Lauffer. You will be involved in developing innovative genetic therapies, creating computational tools, and standardizing therapeutic actionability assessments. Collaboration with national and international initiatives such as the MRC Centre of Research Excellence (CoRE) in Therapeutic Genomics and the N=1 Collaborative is expected, offering excellent opportunities for scientific exchange and professional development. This is an ideal position for a researcher keen on translational research and contributing to building a new research team.

How to Apply:

Online applications are required and must include a full academic CV with a publication list and a Supporting Statement. The Supporting Statement should act as a cover letter and clearly detail how you meet each of the selection criteria outlined in the job description.

Last Date for Apply: Friday, 31 July 2026, 12:00 midday.

Additional Information:

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