Postdoctoral Research Fellow – Mout Lab (Immunobiology), Cincinnati Children’s Hospital Medical Center, USA

Summary

A postdoctoral position is available in Dr. Rubul Mout’s laboratory within the Division of Immunobiology, Division of Oncology, and the Center for Stem Cell and Organoid Medicine (CuSTOM) at Cincinnati Children’s Hospital Medical Center (CCHMC). The Mout Lab focuses on developing and applying cutting-edge protein-based technologies to enhance immune function, control cell signaling, and advance next-generation cancer vaccines and immunotherapies.

Title

Postdoctoral Research Fellow (Mout) – Division of Immunobiology

Job Requisition ID: JR223504

The successful candidate will gain hands-on training, scientific independence, and mentorship while working at the intersection of computational protein design, cell biology, stem cell biology, and translational immunology.

Designation

• Role / Title: Postdoctoral Research Fellow
• Job Category: Fellow & Resident / Biomedical Research
• Employment Type: Regular, Full-Time (1.0 FTE / 40 hours per week)

Overview Table

Research Area

The laboratory integrates computational protein design with stem cell biology and immunology to understand and control immune development and signaling. Key focus areas include:

• De Novo Protein Design & Humanization: Engineering custom proteins and assemblies for targeted therapeutic applications.
• Cancer Immunotherapy: Enhancing T-cell function and persistence using designed agonist proteins.
• Immuno-Aging: Rejuvenating T-cell development and immune regeneration.
• Cancer Vaccines: Developing and programming rare dendritic cell populations for vaccine delivery.

Location

• Campus: Burnet Campus (Location S)
• Address: Cincinnati, Ohio, United States

Eligibility & Qualifications

Required:

• Education: Ph.D., M.D., or equivalent doctoral degree in Biology, Immunology, Biochemistry, Molecular Biology, Bioengineering, or a related biomedical discipline.
• Strong commitment to scientific inquiry and project leadership.

Preferred:

• Demonstrated interest or background in computational/experimental protein engineering, immunology, stem cell biology, or cancer immunotherapy.
• Proven track record of research accomplishments (such as peer-reviewed publications or conference presentations).
• Proficiency in experimental design, critical analysis of data, and scientific communication.

Job Description & Key Responsibilities

• Experimental Execution & Design: Formulate hypotheses, design and execute laboratory experiments, troubleshoot assays, and analyze complex datasets.
• Independent Scientific Development: Develop critical thinking skills, long-term project planning, and specific aims to transition toward scientific independence.
• Scientific Communication: Prepare, draft, and edit manuscripts, scientific reports, abstracts, and grant applications. Present research findings at lab meetings, departmental seminars, and scientific conferences.
• Quality Assurance & Compliance: Ensure reproducibility and accuracy of assays and protocols. Maintain compliance with institutional guidelines (e.g., ORCRA, Infection Control, biosafety protocols).
• Mentorship & Collaboration: Participate in intellectual discussions across departments, provide guidance to junior research staff/students, and assist in administrative laboratory tasks.

How to Apply

1. Visit the Cincinnati Children’s Careers Portal.
2. Search for Requisition ID: JR223504.
3. Create/log into your Workday candidate account.
4. Upload your Curriculum Vitae (CV), a Cover Letter / Statement of Research Interests, and contact details for 2–3 professional references.
5. Complete and submit the online application form.

Last Date for Apply

• Application Deadline: Open until filled / Rolling basis(Candidates are strongly advised to apply as early as possible, as applications are reviewed on a rolling basis).

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