PhD Studentship – Neuroscience: Embark on a groundbreaking PhD journey at the University of Exeter’s Department of Clinical and Biomedical Sciences. This fully-funded studentship, sponsored by the Faculty of Health and Life Sciences, awaits a passionate individual to delve into the neurodevelopmental functions of the histone lysine demethylase KDM5B. Led by esteemed supervisors Prof. Albert Basson, Prof. Jon Brown, Dr. James Chelliah, and Dr. Rosie Bamford, this project promises a holistic exploration of gene variants associated with neurodevelopmental disorders. The selected candidate will receive Home tuition fee coverage and an annual tax-free stipend of at least £18,622 for a 3-year full-time commitment.
PhD Studentship – Neurodevelopmental Functions of the Histone Lysine Demethylase KDM5B, Neuroscience, Epigenetics (Ref: 5027)
Designation: PhD Researcher
Research Area: Neuroscience, Epigenetics
Location: Department of Clinical and Biomedical Sciences, St Luke’s Campus, Exeter
Eligibility/Qualification: Prospective candidates should:
- Hold or anticipate receiving a First or Upper Second Class UK Honours degree or equivalent in a relevant scientific or technological field.
- Demonstrate a strong academic background, with a focus on neuroscience, genetics, or a related discipline.
- Exhibit proficiency in English (if not a native English speaker).
- Possess an inquisitive mind, prior research experience, and a genuine interest in neurodevelopmental disorders.
Job Description: This PhD project involves:
- Identification of brain regions and cell types affected by KDM5B deficiency using single-cell genomics, immunostaining, and conditional gene deletion approaches.
- Definition of synaptic and circuit abnormalities in KDM5B-deficient mouse models through acute and in vivo electrophysiological approaches.
- Targeting and identification of mechanisms responsible for neurodevelopmental phenotypes, with a focus on potential therapeutic interventions.
How to Apply: Interested candidates should submit their applications through the online application portal, including:
- CV
- Letter of application outlining academic interests, prior research experience, and reasons for pursuing the project.
- Transcript(s) with details of subjects studied and grades/marks obtained.
- Names of two referees familiar with the applicant’s academic work.
For English proficiency requirements and other details, refer to the guidance.
Last Date for Apply: 28th February 2024
Interviews will be conducted virtually or on the University of Exeter Streatham Campus in March/April 2024. For project-specific inquiries, contact the main supervisor. General application queries can be directed to pgrapplicants@exeter.ac.uk or by phone.
Summary:
- Application Deadline: 28th February 2024
- Value: Full coverage of Home tuition fees and an annual tax-free stipend of at least £18,622 for 3 years full-time or pro-rata for part-time study.
- Duration of Award: 3 years
- Contact: PGR Admissions (pgrapplicants@exeter.ac.uk)
