This post-doctoral position is available at the Department of Biochemistry and Immunology at the Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), focusing on how ubiquitination pathways regulate genome maintenance in Leishmania.
Post-Doctoral Fellowship: Leishmania Genome Research, Universidade de São Paulo, Brazil
Job Overview
| Field | Details |
| Designation | Post-Doctoral Fellow (PD) |
| Research Area | Molecular Biology / Cell Biology / Genome Biology / Parasitology |
| Location | Ribeirão Preto, Brazil |
| Number of Vacancies | 1 |
| Stipend | R$ 12.570,00 |
| Application Deadline | August 22, 2026 |
Job Description
The successful candidate will join a FAPESP Young Investigator project to investigate how RING factors involved in ubiquitination pathways regulate genome maintenance and plasticity in Leishmania.
Key responsibilities include:
- Generating and characterizing mutant strains using CRISPR/Cas9 and DiCre systems.
- Analyzing cell cycle progression via flow cytometry.
- Evaluating DNA damage through microscopy, immunoblotting, and ChIP-seq (chromatin immunoprecipitation sequencing).
- Utilizing bulk and single-cell genomic sequencing to investigate mosaic aneuploidy.
Eligibility & Qualifications
Mandatory Requirements:
- Doctoral degree (Ph.D.) completed within the last 7 years in Molecular Biology, Biochemistry, Genetics, Cell Biology, Parasitology, Microbiology, Biotechnology, or related fields.
- Commitment to full-time dedication to the project.
- Demonstrated experience in molecular/cell biology and the cultivation of microorganisms/unicellular eukaryotes.
- Proficiency in scientific reading, writing, and communication in English.
- Ability to analyze/interpret experimental data and familiarity with bioinformatics/genomic analysis tools.
Desirable Skills:
- Prior experience with Leishmania or other trypanosomatids.
- Expertise in CRISPR/Cas9, DiCre, ChIP-seq, proteomics, and comparative genomics.
- Programming skills (R or Python).
- Experience in student mentorship and team collaboration; co-authorship in scientific manuscripts.
How to Apply
Interested candidates should send an email to jezieldamasceno@fmrp.usp.br with the subject line: “Pos Doutorado – Ubiquitination Leishmania”.
Your application must include:
- A cover letter (max. 2 pages).
- Doctoral degree certificate.
- Academic transcripts from doctoral studies.
- Curriculum Vitae (max. 4 pages).
- Two professional references (include name, institutional affiliation, and current email address).
For further details on FAPESP requirements, please consult the official FAPESP Post-Doctoral fellowship guidelines.
