Summary
Utrecht University is recruiting a highly motivated and experienced Postdoctoral Researcher to join the multidisciplinary research team led by Dr. Fabio Marino within the Biomolecular Mass Spectrometry and Proteomics division. The position focuses on developing and applying state-of-the-art mass spectrometry (MS)-based immunopeptidomics and proteomics workflows for target identification, quantification, and validation to advance cancer immunotherapy and precision medicine.
Postdoc Position in Clinical Immunopeptidomics and Proteomics, Utrecht University, Netherlands
Designation
- Position Title: Postdoctoral Researcher
Overview Table
| Parameter | Details |
| Employer | Utrecht University |
| Faculty | Faculty of Science |
| Department | Department of Pharmaceutical Sciences (Utrecht Institute for Pharmaceutical Sciences) |
| Research Group | Biomolecular Mass Spectrometry and Proteomics (Dr. Fabio Marino’s Lab) |
| Working Hours | 36 to 40 hours per week |
| Contract Duration | Initial 1-year contract |
| Gross Monthly Salary | €3,546 – €5,538 (Scale 10, CAO NU) |
| Benefits | 8% holiday pay, 8.3% year-end bonus, pension scheme, flexible leave |
| Application Deadline | 31 August 2026 |
Research Area
- Mass Spectrometry–Based Proteomics
- Clinical Immunopeptidomics & Proteogenomics
- Antigen Discovery & T-Cell Recognition Mechanisms
- Cancer Immunotherapy & Translational Medicine
Location
- Address: Heidelberglaan 8, 3584 CS Utrecht, The Netherlands
Eligibility / Qualifications
Required Qualifications & Experience
- Education: PhD in Proteomics, Analytical Chemistry, Biochemistry, or a related field.
- Technical Skills:
- Proven hands-on experience with mass spectrometry–based proteomics/immunopeptidomics in clinical or translational settings.
- Demonstrated expertise in Data-Independent Acquisition (DIA) and Parallel Reaction Monitoring (PRM).
- Hands-on knowledge of quantitative proteomics workflows, data normalization, quality control strategies, and complex MS dataset interpretation.
- Track Record: Publication record in peer-reviewed journals in relevant fields.
- Soft Skills: Excellent teamwork and communication abilities.
Preferred Qualifications & Experience
- Experience with structural biology and cross-linking mass spectrometry.
- Skills in workflow automation and reproducible data analysis pipelines.
Job Description & Key Responsibilities
As a Postdoctoral Researcher, you will play a key role in advancing clinical antigen discovery and precision medicine initiatives. Key responsibilities include:
- Designing and executing mass spectrometry–based workflows to identify and quantify disease-associated antigens from clinical specimens.
- Developing, optimizing, and applying DIA- and PRM-based proteomics methods.
- Conducting quantitative data analysis, normalization, quality control, and statistical interpretation of proteomics datasets.
- Contributing to biomarker and antigen validation studies across diverse clinical cohorts.
- Collaborating with clinicians, computational biologists, and translational researchers across academic, clinical, and industrial networks.
- Supporting method development, data interpretation, manuscript preparation, and grant writing.
How to Apply
- Visit the official Utrecht University Job Portal and click the “Apply now” button.
- Prepare and submit the following documents in English:
- Letter of Motivation
- Curriculum Vitae (CV)
- References: Names, telephone numbers, and email addresses of at least two professional references.
Note: Applications are reviewed on a rolling basis, and the position may close earlier if a suitable candidate is identified. Knowledge security screening may form part of the selection process.
Contact Information
- Job Inquiries: Celine Miedema (
t.c.miedema@uu.nl) - Application Procedure Questions:
science.recruitment@uu.nl
Last Date for Apply
- 31 August 2026 (or until filled)
