Postdoctoral Fellow – Cancer Drug Resistance, Cambridgeshire, UK

Postdoctoral Position in UK United Kingdom

Postdoctoral Fellow – Cancer Drug Resistance: Join us in the pursuit of improving human health and advancing our understanding of life on Earth. The Wellcome Sanger Institute in Hinxton, Cambridgeshire, is offering a full-time, 3-year fixed-term position for a highly-motivated Postdoctoral Research Fellow. The focus of this role is to investigate genetic mechanisms of drug resistance in lung cancer using state-of-the-art CRISPR/Cas9-based screening technologies. By employing gene editing techniques, coupled with single-cell transcriptomics, the Fellow will contribute to deepening our understanding of cancer drug resistance mechanisms and developing novel therapeutic strategies.

Designation: Postdoctoral Fellow

Research Area: Cancer Drug Resistance

Location: Hinxton, Cambridgeshire


  • PhD in a biological science.
  • Proven track record of scientific productivity.
  • Experience in mammalian cell culture, single-cell RNA sequencing, and molecular biology techniques (PCR, cloning).
  • Proficiency in preparing libraries for next-generation sequencing.
  • Strong computer literacy.
  • Effective teamwork and communication skills.
  • Ability to work independently, adapt to changing priorities, and maintain high scientific standards.

Job Description: The Postdoctoral Research Fellow will:

  • Execute large-scale screens and single-cell sequencing experiments.
  • Analyze data and present findings internally and externally.
  • Write high-quality publications.
  • Collaborate with a multidisciplinary team.
  • Investigate genetic mechanisms of drug resistance in lung cancer using CRISPR/Cas9-based technologies.

How to Apply: Interested candidates should submit their CV and a cover letter outlining their suitability for the role to Dr. Matt Coelho ( The application deadline is 6th March 2024.

Last Date for Apply: 6th March 2024

Additional Information:

  • Salary: £38,000 – £49,156 (dependent on skills and experience)
  • Contract Duration: 3 years
  • Contact: Dr. Matt Coelho ( for further information.



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