Postdoctoral Fellow – Downward Lab, Francis Crick Institute, UK

Postdoctoral Position in UK United Kingdom

Postdoctoral Fellow – Downward Lab: The Francis Crick Institute is seeking a talented and motivated Postdoctoral Fellow to join Julian Downward’s laboratory, which focuses on the mechanisms by which mutant oncogenes drive tumor formation and developing more effective cancer treatments. The successful candidate will have a strong background in tumor immunology and experience using mouse models in cancer research.

Summary Table:

Job TitlePostdoctoral Fellow – Downward Lab
DesignationPostdoctoral Training Fellow
Research AreaOncogene Biology, Tumor Immunology
Eligibility/QualificationPhD in relevant subject area (or near completion)
Job TypeFull-time, fixed-term for 4 years
SalaryFrom £43,210 with benefits, subject to skills and experience
Reports toJulian Downward
Closing Date31/Jul/2024 23.59 GMT

Designation: Postdoctoral Training Fellow

Research Area: Oncogene Biology, Tumor Immunology

Location: London


  • PhD in a relevant subject area or in the final stages of PhD submission
  • Good knowledge and experience in cancer biology, molecular cell biology, and immunology
  • Technical expertise in tumor immunology, such as immune phenotyping by FACS, single-cell sequencing, multiplexed spatial imaging, or mass cytometry
  • Experience in the use of mouse models in cancer or immunology research
  • Experience in bioinformatics for analyzing large biological datasets
  • Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals
  • Evidence of data presentation at scientific meetings
  • Ability to work independently and within a team
  • Proactive in innovation and problem-solving
  • Experience in experimental design

Job Description: The Postdoctoral Fellow will lead their own projects and contribute to collaborative projects within the lab and with external collaborators. The focus will be on understanding how RAS oncogenes drive tumor formation and exploring therapeutic strategies, particularly in relation to tumor immune microenvironment (TiME) and drug resistance. The role involves utilizing immune competent syngeneic mouse models, conducting multiplexed imaging and spatial transcriptomics, and analyzing immune responses to identify effective combination therapies.

How to Apply: Interested candidates should apply through the Francis Crick Institute’s career portal by submitting their CV, a cover letter detailing their research experience and interest in the position, and contact information for at least two references.

Last Date for Apply: 31/Jul/2024 23.59 GMT



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