Postdoctoral Fellow – Spector Lab: The Spector Lab at Cold Spring Harbor Laboratory (CSHL) is seeking a highly motivated Postdoctoral Fellow to investigate the roles of Long Non-Coding RNAs (lncRNAs) in pluripotency and differentiation. This research builds on RNA-seq findings in mouse embryonic stem cells and aims to characterize functional lncRNAs using advanced genomic and molecular biology approaches. The position offers a unique opportunity to work in a world-class research environment and contribute to cutting-edge discoveries in gene regulation and developmental biology.
Summary Table:
| Category | Details |
|---|---|
| Position | Postdoctoral Fellow – Spector Lab |
| Designation | Postdoctoral Research Fellow |
| Research Area | Long Non-Coding RNAs (lncRNAs), Pluripotency, Differentiation |
| Location | Cold Spring Harbor Laboratory, New York, USA |
| Salary | $74,300.00 per annum |
| Eligibility | PhD (completed or near completion); experience in relevant techniques |
| Application Deadline | Within one year of PhD award; early application encouraged |
Designation:
Postdoctoral Research Fellow
Research Area:
- Long Non-Coding RNAs (lncRNAs)
- Pluripotency and Differentiation
- Gene Regulation and Reprogramming
- Functional Genomics and CRISPR Technologies
Location:
Cold Spring Harbor Laboratory (CSHL)
Cold Spring Harbor, New York, USA
Eligibility/Qualifications:
- PhD in Molecular Biology, Genetics, Developmental Biology, or related field (completed or near completion).
- Preferred experience in:
- Mouse embryonic stem cell culturing and differentiation
- Molecular biology techniques
- Genomic analysis (e.g., RNA-seq)
- CRISPR-based approaches
- Mouse models
Job Description:
The selected candidate will:
- Investigate the function of lncRNAs identified through RNA-seq screens in pluripotent and differentiating cells.
- Utilize innovative methodologies such as single-molecule fluorescence in situ hybridization (smFISH), immunofluorescence microscopy, and CRISPR-based tools.
- Work closely with Dr. David L. Spector and the lab team to design and conduct experiments aimed at uncovering the mechanisms by which lncRNAs regulate cellular states.
- Publish findings in high-impact journals and present research at conferences.
Key Publications from the Spector Lab:
- Genome Research (2009) – MEN e/b lncRNAs in muscle differentiation
- Current Opinion in Cell Biology (2014) – lncRNAs and nuclear function
- Developmental Cell (2022) – Platr4 lncRNA in cardiogenic lineage
- Frontiers in Cell and Developmental Biology (2022) – lncRNA visualization in embryos
How to Apply:
Interested candidates should:
- Send the following documents to Dr. David L. Spector at spector@cshl.edu:
- Curriculum Vitae (CV)
- Statement of research accomplishments and interest
- Contact details for three references
- Submit an online application at: Postdoc-Spector Lab Position 01698
Last Date to Apply:
Applications are open for candidates within one year of PhD completion. Early applications are strongly encouraged as the position will remain open until filled.
Additional Information:
Cold Spring Harbor Laboratory (CSHL) is a globally recognized hub for biomedical research and the home of 8 Nobel laureates. The lab fosters a collaborative and inclusive scientific environment and provides access to cutting-edge research infrastructure and international networking opportunities through its renowned Meetings and Courses program.
Compensation & Benefits:
- Annual salary of $74,300.00
- Comprehensive health benefits
- Retirement plans
- Paid time off
- Wellness and recognition programs
EOE Statement: CSHL is an Equal Opportunity Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or veteran status.
Contact Information:
Douglas Ricciardi
Associate, Human Resources
Cold Spring Harbor Laboratory
Phone: (516) 367-6984
Fax: (516) 367-6850
Email: ricciardi@cshl.edu
