Summary:
The University of British Columbia’s Michael Smith Laboratories invites applications for a Postdoctoral Research Fellow in Single-Molecule Biophysics and Nanomedicine. The position focuses on advancing analytical technologies for RNA-based therapeutics in a collaborative research program.
Postdoctoral Fellowship in Single-Molecule Biophysics and Nanomedicine
Designation:
Postdoctoral Research Fellow
Key Details:
| Field | Details |
|---|---|
| Research Area | Single-Molecule Biophysics and Nanomedicine |
| Location | UBC Vancouver Campus – Vancouver, BC, Canada |
| Expected Salary | $60,000/year |
| Job Posting End Date | June 4, 2026 |
| Job End Date | June 30, 2027 |
Eligibility/Qualification:
- PhD in Physics, Biophysics, Bioengineering, Chemistry, or a related field.
- Strong experimental and hands-on background in quantitative science.
- Experience with data analysis and scientific programming.
- Preferred: Experience in single-molecule or fluorescence microscopy, microfluidics, nanotechnology, or soft matter systems.
- Familiarity with RNA biology or drug delivery systems is a plus.
- Programming skills in Python, MATLAB, or similar, and experience with mammalian cell culture are desirable.
Job Description:
The successful candidate will work under Dr. Sabrina Leslie to:
- High-resolution characterization of LNP formulations:
- Generate quantitative datasets of particle size distributions and mRNA payload heterogeneity using advanced CLiC-based methodologies.
- Development of post-formulation labeling strategies:
- Create novel assays for sensitive detection of LNP, mRNA, and other cargo, enabling more flexible workflows.
- Scale-up of measurements using microfluidics and AI-enhanced tools:
- Collaborate with engineers to increase the throughput of assays on a next-generation imaging platform.
How to Apply:
Interested applicants should submit the following materials:
- Curriculum Vitae
- Cover letter describing research experience and interests
- Contact information for 2 to 3 references
Applications should be submitted through the UBC Career Portals.
Last Date to Apply:
June 30, 2026 (Applications accepted until 11:59 PM on the posting end date)
Equity and Diversity Statement:
UBC is committed to building a diverse community. We encourage applications from members of groups marginalized under the B.C. Human Rights Code.
