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Postdoctoral Research Associate in Structural Mass Spectrometry – University of Oxford, UK

Postdoctoral Research Assistant Position in University of Oxford, UK

Summary

The University of Oxford’s Department of Biochemistry is inviting applications for a Postdoctoral Research Associate in Structural Mass Spectrometry. This role involves leading native mass spectrometry research within the Newstead group to study the structure and cellular biology of solute carrier (SLC) transporters.

Job Details

DesignationPostdoctoral Research Associate
Research AreaStructural Mass Spectrometry / Structural Biology
LocationDepartment of Biochemistry, South Parks Road, Oxford OX1 3QU
Salary£42,794 to £47,779 per annum
Contract TypeFull Time, Fixed-Term (Up to 12 months)

Eligibility/Qualification

The successful candidate must meet the following requirements:

  • A PhD/DPhil (or be near completion) in biophysical chemistry, analytical chemistry, structural biology, or a related discipline.
  • Substantial experience in native top-down mass spectrometry using high-resolution hybrid Orbitrap instrumentation (e.g., Thermo Fisher Orbitrap UHMR and Ascend platforms).
  • Expertise in native mass spectrometry sample preparation and advanced fragmentation techniques.
  • Experience in the quantitative analysis of protein modifications, lipid interactions, proteomics, and lipidomics.
  • Proficiency in membrane protein expression and purification.
  • Strong computational and data-analysis skills, preferably with experience in Python.
  • A strong publication record and experience in glycoproteomics or open-source software development is considered advantageous.

Job Description

Reporting to Professor Simon Newstead and Dr. Jo Parker, the post holder will be a key member of the Newstead group located in the Department of Biochemistry and the Kavli Institute for Nanoscience. The primary responsibility is to lead the group’s native mass spectrometry research. This research is part of a broader program investigating how SLC transporters are folded, modified, trafficked, and regulated within mammalian cells.

What We Offer

  • An excellent contributory pension scheme.
  • 38 days of annual leave.
  • Comprehensive childcare services and family leave schemes.
  • Cycle loan scheme and discounted travel options.
  • Access to a wide variety of social and sports clubs.

How to Apply

Applications must be submitted online through the University of Oxford recruitment portal. To apply, please follow these steps:

  1. Visit the recruitment website and search for Vacancy ID 189364.
  2. Upload a current Curriculum Vitae (CV).
  3. Upload a supporting statement detailing how you meet the selection criteria with specific examples of your skills and experience.
  4. Provide contact details for two referees.

For further enquiries, contact: recruitment@bioch.ox.ac.uk

Last Date for Apply

The closing date for applications is 12.00 noon on Monday 9th November 2026.

Apply Link

Apply Online via University of Oxford Portal

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