Postdoctoral Research Associate in Cell Signalling, University of Oxford, United Kingdom

Postdoctoral Research Assistant Position in University of Oxford, UK

Research Associate in Cell Signalling: The University of Oxford’s Department of Biochemistry is seeking a dedicated Postdoctoral Research Associate to explore the molecular mechanisms guiding the Wnt/beta-catenin signalling pathway. This role involves a multidisciplinary approach including biochemistry, cell biology, and structural biology.

Postdoctoral Research Associate in Mechanisms of Cell Signalling

Designation:

Postdoctoral Research Associate

Research Area:

Cell Signalling, Biochemistry, Cell Biology, Structural Biology

Location:

Oxford, United Kingdom

Eligibility/Qualification:

  • A PhD/DPhil or near completion of a PhD/DPhil in Biochemistry, Cell Biology, or a related discipline.
  • Significant experience in molecular biology techniques, particularly recombinant DNA techniques.
  • Proficiency in expression and purification of recombinant proteins and biochemical/biophysical characterization methods.
  • Knowledge and experience in mammalian cell culture and associated techniques.
  • Strong organizational skills with ability to prioritize and multitask.
  • Excellent oral and written communication skills, capable of writing for publication and presenting research.

Job Description:

The successful candidate will:

  • Investigate the mechanisms of Wnt pathway activation and termination at the plasma membrane.
  • Build on previous successes in the biochemical reconstitution of the beta-catenin destruction complex.
  • Utilize state-of-the-art tools such as CRISPR approaches and super-resolution microscopy to study cytoplasmic signal transduction protein regulation.
  • Work both independently and as part of a collaborative team to achieve research objectives.

How to Apply:

Interested applicants should apply online via www.recruit.ox.ac.uk with Vacancy ID 183362. Candidates are required to upload:

  • Curriculum Vitae
  • Supporting statement detailing how they meet the selection criteria, including examples of relevant skills and experiences.
  • Contact information for two referees.

Last Date for Apply:

Applications must be submitted by 12:00 noon on Monday, 15th December 2025. Late submissions will not be considered.

For further details or inquiries, contact recruitment@bioch.ox.ac.uk.


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