PhD Position – Organ-Organ Interactions: The University of Twente, Applied Stem Cell Technologies group, invites applications for a full-time PhD position to explore organ-organ interactions on chip. This position offers a unique opportunity to delve into the molecular nature of innervation-driven organ-organ interaction using stem cell-based organ-on-chip technology. The research aims to study physiological signaling, drug responses, and interactions in a well-regulated manner, providing insights into microenvironmental conditions. The successful candidate will work collaboratively with the BIOS Lab-on-a-Chip group at the University of Twente.
Designation: PhD Position
Research Area: Organ-Organ Interactions on Chip
Location: University of Twente, Enschede, Netherlands
Eligibility/Qualification:
- MSc degree in (stem cell) biology, neurobiology, or associated field.
- In-depth expertise in (stem) cell biology and biochemistry.
- Affinity with microfluidic chip design and fabrication.
- Experience with differentiation protocols for creating organoid cultures.
- Proficiency in English (IELTS test results minimum score 6.5 or TOEFL iBT minimum score 90 if required).
- Strong communication skills and the ability to work collaboratively in a team.
Job Description:
PhD Position – Organ-Organ Interactions on Chip
- Use human induced pluripotent stem cell-derived organoids and innervating structures on a microfluidic chip to investigate organ-organ interactions.
- Select relevant organs and employ differentiation procedures to create organoids.
- Culture organoids in microfluidic devices, validate identity, maturation stage, and functional activity using biomarkers, imaging, and electrophysiological read-outs.
- Assist in creating microfluidic devices for innervation, optimizing their design based on physiological relevance and anatomical orientation.
- Validate functional innervation of target organs and investigate the regulatory role of innervation on organ-organ interaction using integrated sensors.
How to Apply: Interested candidates should submit their application via email to Prof. Dr. Kerensa Broersen (k.broersen@utwente.nl). The application should include:
- Curriculum vitae
- Letter of motivation
- Grades of BSc and MSc courses
- IELTS or TOEFL score (if required)
- Contact information of two references
Last Date for Apply: 31 January 2024
Disclaimer: The information provided is based on the source, and applicants are encouraged to verify details and check for updates on the official University of Twente website for the most accurate and up-to-date information.
