PhD Studentship in Biorelevant Metal Complexes : The University of Warwick invites applications for a PhD studentship focused on developing innovative biorelevant metal complexes for cancer treatment. This project seeks to address the limitations of traditional platinum-based drugs by exploring novel metal complexes as potential hypoxic activated prodrugs.
PhD Studentship in Biorelevant Metal Complexes as Potential Hypoxic Activated Prodrugs for the Treatment of Cancer
Designation
PhD Studentship
Table of Information
| Category | Details |
|---|---|
| Research Area | Biorelevant metal complexes and drug discovery in cancer treatment |
| Location | University of Warwick, Coventry, UK |
| Eligibility/Qualification | – Good degree (at least 2.1 or equivalent) in chemistry or a relevant discipline. – Strong research interest in drug discovery and chemical biology (no prior biology experience required). |
| Funding Amount | UKRI recommended stipend rate for 3.5 years of home fees and stipend for UK students. Open to overseas students with additional financial means required. |
| Supervisor | Dr. Rianne M. Lord |
| Last Date for Apply | Open until suitable candidate is identified; early applications encouraged. |
Research Area
The primary focus is on designing and developing biorelevant metal complexes that can act as effective hypoxic activated prodrugs, targeting low oxygen environments typical of certain cancer cells.
Description
This research project addresses the significant drawbacks of existing platinum-based metallodrugs in cancer therapy, including non-selectivity and patient side effects. The candidate will engage in laboratory work to synthesize new metal complexes, conduct in-depth cellular studies to assess toxicity and redox potentials, and develop potential prodrugs that can be activated in hypoxic conditions. The successful applicant will join an interdisciplinary collaboration supported by the Department of Chemistry and will receive comprehensive training in synthesis, analysis, and cell culture techniques.
How to Apply
Interested candidates should first contact Dr. Rianne M. Lord via email at Rianne.lord@warwick.ac.uk with the following documents:
- A copy of your CV
- A covering letter outlining your research interests and motivation for applying.
For more information on the formal application procedure, visit University of Warwick Postgraduate Applications.
Last Date for Apply
The application process remains open until a suitable candidate is identified. Early application is strongly encouraged.
