Postdoc Position in Glioblastoma Neurobiology: We are seeking a highly motivated postdoctoral researcher for an exciting collaboration between the Bio Engineering Laboratory at ETH Zurich and the University Hospital Heidelberg / German Cancer Research Center. This position focuses on understanding glioblastoma (GB) and its interaction with neuronal circuits, aiming to discover new therapeutic targets.
Postdoc Position in Glioblastoma Neurobiology and Neuron-Tumor Connectivity
Designation
Postdoctoral Researcher
Table
| Details | Information |
|---|---|
| Research Area | Glioblastoma Neurobiology and Neuron-Tumor Connectivity |
| Location | ETH Zurich, Basel / University Hospital Heidelberg |
| Eligibility/Qualification | PhD in neuroscience, biology, bioengineering, or a related field; strong background in cell culture and electrophysiology; experience with transcriptomic methods is advantageous |
| Duration | Up to 3 years |
| Funding | Full position (100%) |
Job Description
As a postdoc, you will:
- Establish and characterize human neuron-tumor co-cultures using iPSC-derived neurons and patient-derived GB models on High-Density Microelectrode Arrays (HD-MEAs).
- Conduct longitudinal electrophysiological recordings to assess how tumor invasion alters neuronal network activity at both single-cell and population levels.
- Utilize spatial transcriptomic techniques to map gene expression changes in neurons connected and unconnected to tumors.
- Integrate functional and transcriptomic datasets to uncover molecular mechanisms underlying GB-neuron interactions.
- Assist in drug screening efforts targeting neuron-tumor connectivity.
How to Apply
Interested candidates should submit their application, including a CV, cover letter, and references, via the ETH Zurich application portal.
Last Date to Apply
Until position filled
Additional Benefits
- Access to state-of-the-art HD-MEA technology and microscopy facilities.
- Collaborative environment within an international team.
- Opportunity for professional development and contribution to impactful research.
- Numerous benefits, including public transport season tickets, sports options, childcare, and attractive pension benefits.
Join us in this pioneering project at ETH Zurich and contribute to significant advancements in glioblastoma research!
