Summary:
Imperial College London is inviting applications for a full-time, fixed-term position as a Research Associate in Chemical Biology. This opportunity is within the Department of Chemistry, specifically in the Micklefield Lab, which is focused on developing bio-inspired, sustainable methods to build therapeutic molecules. The research involves interdisciplinary work at the Chemistry-Biology interface, addressing significant challenges such as antimicrobial resistance (AMR) and neglected diseases.
Research Associate in Chemical Biology, London, UK
Designation:
Research Associate in Chemical Biology
Research Area:
- Biosynthesis and biosynthetic pathway engineering
- Biocatalysis and integrated catalysis
- Enzyme discovery, characterisation, and engineering
- Enzymatic synthesis
- Organic chemistry, molecular microbiology, and genetics
Location:
White City Campus, Imperial College London, London, UK
Eligibility/Qualification:
- PhD in Chemistry, Biochemistry, or a closely related discipline.
- Practical experience in enzyme discovery, characterisation, and enzyme engineering is desirable.
- Knowledge in biocatalysis, enzymatic synthesis, directed evolution, biosynthesis of natural products, and biosynthetic pathway engineering.
- Familiarity with microbiology, bioinformatics, genome mining, organic synthesis, and analytical methods would be beneficial.
Job Description:
As a Research Associate, you will contribute to the development of sustainable bio-inspired methodologies for creating molecules with therapeutic potential. This includes:
- Engineering biosynthetic pathways to provide novel bioactive natural products, focusing on antibiotics to combat antimicrobial resistance (AMR).
- Exploring biocatalysis and integrated catalysis, involving enzyme discovery, characterisation, and engineering for enzymatic synthesis.
- Merging chemo- and biocatalysis for developing streamlined routes to pharmaceuticals and other valuable products.
Salary:
£49,017 to £57,472 per annum
How to Apply:
Interested candidates should apply online through the Imperial College London recruitment portal. For additional inquiries, contact Professor Jason Micklefield via email at j.micklefield@imperial.ac.uk.
Last Date for Apply:
30th April 2026
For more information about the Micklefield Lab, please visit:
