Summary
A fully funded 36-month PhD scholarship is available at the CNRS Coordination Chemistry Laboratory, supported by the Foundation “Vaincre Alzheimer.” This interdisciplinary research project focuses on developing innovative copper-targeting ligands as a therapeutic strategy for Alzheimer’s disease. The position offers an excellent opportunity to work at the interface of chemistry, biology, and neuroscience.
PhD Scholarship Opportunity in Alzheimer’s Therapeutic Chemistry, France
Designation
PhD Research Scholar / Doctoral Candidate
Research Area
- Bioinorganic Chemistry
- Alzheimer’s Disease Research
- Therapeutic Chemistry
- Cellular & Molecular Biology
- Neurochemistry
Location
- Toulouse – Coordination Chemistry Laboratory (LCC)
- Strasbourg – Institute of Cellular and Integrative Neurosciences
Eligibility / Qualification
- Master’s degree (or equivalent) in:
- Cellular Biology
- Molecular Biology
- Biochemistry
- Pharmacology or related fields
- Strong interest in:
- Chemistry–Biology interface
- Therapeutic research
- Candidate should be:
- Motivated and persevering
- Interested in multidisciplinary research environments
Job Description
The selected candidate will work on evaluating novel traceable copper ligands as therapeutic agents for Alzheimer’s disease. Key responsibilities include:
- Testing newly synthesized ligands capable of removing copper from β-amyloid complexes
- Conducting in vitro and cell-based (in vivo model) experiments
- Studying:
- Cellular uptake of ligands
- Copper distribution in cells
- Cell viability and inflammation markers
- Investigating reduction of oxidative stress caused by reactive oxygen species (ROS)
- Monitoring ligand behavior using time-resolved confocal microscopy
- Collaborating across institutions in Toulouse and Strasbourg
How to Apply
Applicants must submit the following documents:
- Updated CV (including academic history)
- Two references
- Cover letter
- Most recent academic transcripts
Contact for Application:
Dr. Charlène Esmieu
📧 charlene.esmieu@lcc-toulouse.fr
Last Date for Apply
- Open Now
Additional Information
- Start Date: 1st July 2026
- Funding Duration: 36 months
- Supervision by:
- Dr. Charlène Esmieu
- Dr. Christelle Hureau
- Collaboration with Dr. Nicolas Vitale (Strasbourg)
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