Summary
The laboratory of Dr. Georgia Isom at the Sir William Dunn School of Pathology, University of Oxford, is seeking a motivated Postdoctoral Research Assistant. This exciting 2-year project aims to uncover the molecular machinery that transports sphingolipids to the surface of Gram-negative bacteria by combining cryo-electron microscopy, native mass spectrometry, proteomics, and bacterial cell biology.
Postdoctoral Research Assistant in Structural Biology, University of Oxford, UK
Key Job Details
| Feature | Details |
| Designation | Postdoctoral Research Assistant |
| Research Area | Structural Biology / Bacterial Membrane Biology |
| Location | University of Oxford, United Kingdom |
| Employment Type | Fixed-term (2 years in the first instance, with funds to extend) |
| Start Date | Autumn/Winter 2026 |
| Application Deadline | Noon on Friday, 31 July 2026 |
Eligibility & Qualification
- Education: Must hold, or be close to the completion of, a PhD in structural biology.
- Experience: Proven experience in solving high-resolution structures using single-particle cryo-EM.
- Skills: Highly motivated, well-organized, and capable of working both independently and collaboratively as part of a team.
Job Description
As the successful candidate, you will drive this research project by combining structural and mechanistic approaches to identify and characterize bacterial sphingolipid transport systems.
Key Responsibilities:
- Determine high-resolution single-particle cryo-EM structures of sphingolipid transporters.
- Assess sphingolipid-transporter interactions and evaluate the role of sphingolipids in membrane homeostasis.
- Utilize a multidisciplinary approach combining mass spectrometry and cellular electron microscopy methods.
How to Apply
Applications must be submitted online through the university’s portal.
- Required Documents: You will need to upload a CV and a supporting statement as part of your online application.
- Inquiries: Informal enquiries can be directed to Dr. Georgia Isom via email at georgia.isom@path.ox.ac.uk.
- Official Link: For more comprehensive details and to submit your application, visit the Instruct-ERIC Job Posting.
Application Deadline: All submissions must be received before noon on Friday, 31st July 2026. Interviews will be conducted shortly after this deadline.
