Summary
The Biozentrum of the University of Basel is offering a fully funded PhD position within the research group of Prof. Knut Drescher. This multidisciplinary project is part of the Swiss National Competence Center in Research (NCCR) “AntiResist” and focuses on combating the global antibiotic resistance crisis by developing innovative biosensors to measure antibiotic concentrations at infection sites.
PhD Position Available: Antibiotic Biosensor Protein Engineering, University of Basel, Switzerland
Position Overview
| Detail | Information |
| Designation | PhD Student |
| Research Area | Molecular Microbiology, Biochemistry, and Protein Design |
| Location | Basel, Switzerland |
| Last Date to Apply | August 20, 2026 |
Research Area & Project Details
The project combines computational and experimental approaches to design, engineer, and transform biosensor candidates into fully functional tools within bacterial cells.
Key applications include:
- Developing allosteric biosensors for major classes of antibiotics.
- Performing real-time, high-resolution measurements of antibiotic concentrations at infection sites.
- Monitoring antibiotic dynamics inside bacterial cells across various models, ranging from biofilm treatments to stem-cell-derived organoids and bioengineered tissue infection systems.
Job Description & Benefits
As a PhD student in this role, you will:
- Conduct cutting-edge, multidisciplinary research bridging biophysics, bioinformatics, and molecular biology.
- Analyze large datasets and collaborate closely with core facilities.
- Benefit from being part of the Swiss-wide NCCR AntiResist consortium, providing extensive scientific exchange, networking, and career development opportunities.
Eligibility & Qualifications
- A Master’s degree with a completed research thesis in molecular microbiology, protein biochemistry, protein design, or a closely related discipline.
- High motivation, talent, and a strong interest in the project’s focus.
- Ability to work effectively within an international, diverse, and collaborative team.
How to Apply
Applications must be submitted exclusively through the online system. To apply, you will need to provide a brief statement of your research experience, your interest in the position, a current CV, and contact information for two references.
- Application Portal: Online Submission Form
- Informal Enquiries: Can be directed to Prof. Knut Drescher via email.
- For more information on the lab’s work, you can review the Drescher Lab Publications.
