Tallinn University of Technology (TalTech) Virumaa College is inviting applications for a Postdoctoral Researcher to join a research project focused on developing molecular platforms for nucleic acid delivery. This position offers a unique opportunity to work on mRNA technologies and includes potential research visits to the University of Pennsylvania.
Job Summary
The project focuses on the design, synthesis, and characterization of amphiphilic Janus dendrimers and their influence on molecular self-assembly and mRNA delivery. The primary goal is to develop single-component delivery systems as alternatives to conventional multicomponent lipid nanoparticles.
Designation
Postdoctoral Researcher
Research Area
Organic Chemistry, Supramolecular Chemistry, Chemical Biology, and Pharmaceutical Chemistry.
Location
Tallinn, Estonia (with potential visits to the University of Pennsylvania, USA).
Eligibility/Qualification
Essential Qualifications:
- A PhD in organic chemistry, supramolecular chemistry, chemical biology, pharmaceutical chemistry, or a closely related discipline.
- Strong practical experience in multistep organic synthesis and the preparation of complex molecules.
- Proficiency in the purification and characterization of organic compounds.
- Excellent written and spoken English skills.
- Strong analytical thinking and problem-solving abilities.
Desirable Qualifications:
- Experience in dendrimer chemistry, amphiphilic molecules, or self-assembling systems.
- Knowledge of lipid nanoparticles, nucleic acid delivery, or mRNA technologies.
- Experience with advanced NMR spectroscopy and mass spectrometry.
- A strong record of scientific publications.
Job Description
The successful candidate will contribute to an interdisciplinary research program with the following responsibilities:
- Design and synthesize novel amphiphilic Janus dendrimers and related molecular structures.
- Develop and optimize multistep organic synthesis and purification procedures.
- Characterize compounds using NMR spectroscopy, mass spectrometry, and other analytical methods.
- Investigate structure-property relationships and self-assembly properties.
- Collaborate with project partners on the evaluation of mRNA delivery formulations.
- Prepare scientific publications and present findings at international conferences.
What We Offer
- Two-year employment duration with the possibility of a one-year extension.
- Access to state-of-the-art chemical synthesis and characterization facilities.
- Opportunities for international collaboration and professional development.
- Remuneration commensurate with qualifications and experience.
How to Apply
Interested candidates should submit the following documents to Jasper Adamson at jasper.adamson@taltech.ee:
- A cover letter outlining research background and motivation.
- An academic CV, including a full list of publications.
- A brief description of previous research experience and technical skills.
- Contact details for two academic referees.
Please use the subject line: “Application – Postdoctoral Researcher in Organic and Supramolecular Chemistry.”
Last Date for Apply
December 10, 2026
Apply Link
Apply via Email to Professor Jasper Adamson
