Genome Stability in Ageing: The Institute for Genome Stability in Aging and Disease, located in Cologne, Germany, is seeking highly motivated postdoctoral candidates who are interested in investigating the fundamental role of DNA damage in ageing and how inheritance of stable genomes is regulated. The research focuses on understanding how DNA damage causes ageing and cancer and how genome instability impacts genetic inheritance, with the aim of developing therapeutic strategies aimed at preventing ageing-related diseases.
Designation: Postdoctoral Researcher Research
Area: Investigating the role of DNA damage in ageing and inheritance of stable genomes
Location: Cologne, Germany Institution
Information: Institute for Genome Stability in Aging and Disease, CECAD Research Center, University of Cologne
Qualifications: Applicants should have a PhD degree and a solid background in molecular biology, cell biology, genetics, biochemistry, or bioinformatics.
Job Description: The successful candidate will be involved in research using both genetic and biochemical approaches, primarily in the C. elegans but also in mammalian systems, to investigate the molecular basis of ageing and inheritance. The candidate will work in a highly international academic research environment and will have access to state-of-the-art equipment and facilities.
How to Apply: Interested candidates should send a CV, a letter of intent, a list of publications, and names and addresses of three references to ojoem schumacheratluntkosin e.
Last Date for Applying: Not specified
Selected Publications:
| Full list of publications available at https://igsad.de/schumacher-fab-publications/
| Soltanmohammadi N, Wang S, Schumacher B. Somatic PVK-1/038 signaling inks environmental stress to germ cell apoptosis and heritable euploidy. Nat Commun. 2022 Feb 413(1)701. doi: 10.1038/s41467-022-28225-8.
| Schumacher B, Pothof J, Vijg J, Hoejmakers JHJ. The central role of DNA damage in the ageing process. Nature. 2021 Apr;592(7856)’695-703. doi: 10.1038/541586-021-03307-7.
| Meyer DH, Schumacher B. BIT age: A transcriptome based aging clock near the theoretical limit of accuracy. Aging Cell. 2021 Mar20(3)13320. doi: 10.1111/acel 13320, Epub 2021 Mar 3.
| Wang S, Meyer DH, Schumacher, B. H3me2 reguiates the recovery of proten biosynthesis and homsostass following DNA damage Nat Struct Mol Biol. 2020 doi org/10.1038/541594-020-00513-1 }
| Lopes AFC, Bozek K, Herholz M, Trifunovic A, Rieckher M, Schumacher B#. A C. elegans model for neurodegeneration in Cockayne syndrome. Nucleic Acids Res. 2020, gkaa795, doi org/10.1093/nar/gkaa795 (#co-corresponding authors)
| Schumacher B, Vjg J. Age is n the nucleus. Nat Metab, 2019, doi 10.1038/542255-019-0125-9. Epub 2019 0ct 7
| Ou HL, Kim CS, Uszkoreit S, Wickstrom SA, Schumacher B. Somatic niche cells regulate the CEP-1/p53-mediated
