Summary
Karolinska Institutet invites applications for a doctoral student position focused on intestinal mucosal immunology. This role involves pivotal research into how mucus-producing cell populations shape the properties and functions of intestinal mucus.
Doctoral (PhD) Student Position in Intestinal Mucosal Immunology, Solna, Stockholm County, Sweden
Designation
Doctoral Student (PhD)
| Details | Information |
|---|---|
| Research Area | Intestinal Mucosal Immunology |
| Location | Solna, Stockholm County, Sweden |
| Number of Positions | 1 Full-time equivalent 100% |
| Contract Type | Full-time, maximum 4 years |
Eligibility/Qualification
Required Qualifications:
- Master’s degree in molecular biology, biochemistry, cell biology, biomedical sciences, or a closely related discipline with a strong experimental component.
- Documented experience in experimental laboratory work in relevant areas (cell biology, microbiology, or molecular biology).
- Certification for mouse handling and documented experience in animal work.
- Strong written and oral communication skills in English.
Meritorious:
- Experience with intestinal infection models or microbiology (bacterial or parasitic).
- Experience with single-cell RNA sequencing or other transcriptomic approaches.
- Basic bioinformatics skills (e.g., R or Python) and experience handling large datasets.
- Experience with proteomics, mass spectrometry, and analysis of post-translational modifications.
- Familiarity with advanced imaging techniques (e.g., confocal microscopy).
- Experience with ex vivo tissue assays, preferably intestinal.
Job Description
The doctoral student will investigate how diverse mucus-producing cell populations influence mucus properties and functions. Key responsibilities include:
- Utilizing single-cell RNA sequencing to characterize goblet cell populations.
- Employing ex vivo mucus analysis platforms.
- Studying post-translational modifications using mass spectrometry.
- Conducting experimental work in animal models, including monitoring disease progression under altered conditions.
- Collaborating within the research group and actively engaging in lab activities.
How to Apply
Submit your application, including a personal letter, CV, degree projects, and any documentation supporting your qualifications, through the Varbi recruitment system. Applications can be submitted in English or Swedish.
Last Date for Apply
22nd May 2026
Contact Information:
- Supervisor: Elisabeth Nyström
- Email: elisabeth.nystrom@ki.se
