This is an opportunity for a Direct Doctorate position funded by FAPESP, focusing on the intersection of molecular biology, cell biology, and parasitology.
Ph.D. Opportunity: Genomic Research on Leishmania at FMRP- University of São Paulo, Brazil
Designation
Bolsa de Doutorado Direto (Direct Doctorate Fellowship)
Research Area
Biochemistry, Molecular Biology, Cell Biology, Genome Biology, and Parasitology.
Location
Department of Biochemistry and Immunology, Faculty of Medicine of Ribeirão Preto, University of São Paulo (FMRP-USP), Ribeirão Preto.
Key Details
| Feature | Information |
| Project Title | Dissecando como a ubiquitinação direciona a replicação e a plasticidade do genoma em Leishmania |
| FAPESP Process No. | 2025/10952-6 |
| Number of Positions | 1 |
| Value of Scholarship | R$ 5.790,00 |
| Principal Investigator | Jeziel Dener Damasceno |
Job Description
The successful candidate will work within a FAPESP Young Investigator project investigating how the SCF/CRL1 ubiquitin ligase regulates the DNA replication program in Leishmania.
The research involves:
- Target Characterization: Using genomic engineering (CRISPR/Cas9 and DiCre).
- Experimental Techniques: Cell biology and biochemistry methods, including microscopy, pulldown, ubiquitination assays, and proteomics.
- Bioinformatics: Utilizing tools such as MFA-seq and DNAscent to analyze the functional impact of ubiquitination on genome replication.
Eligibility & Qualification
- Mandatory:
- Scientific motivation and availability for full-time dedication to the project.
- Ability to read and interpret scientific literature in English.
- Undergraduate degree (completed or expected by the start date) in Biological Sciences, Biomedicine, Biotechnology, Biochemistry, Pharmacy, or related fields.
- Approval in the admission exam for the Direct Doctorate program at the Department of Biochemistry and Immunology, FMRP-USP.
- Compliance with FAPESP regulations for Direct Doctorate fellowships.
- Desirable:
- Strong communication, organization, and collaborative skills.
- Prior experience in molecular biology, working with Leishmania or other trypanosomatids, CRISPR/Cas9, DiCre, and microscopy.
- Basic knowledge of bioinformatics and sequencing data analysis.
How to Apply
Interested candidates should send an email to jezieldamasceno@fmrp.usp.br with the subject: “Doutorado Direto – Ubiquitination Leishmania”.
The email must include:
- Full name.
- Two professional references (name, institutional affiliation, and updated email).
- Attached as a PDF:
- Motivation letter (maximum 2 pages).
- Complete academic transcript.
- CV (maximum 4 pages).
Last Date for Application
August 22, 2026
