Summary
The University of Cologne, one of Europe’s largest and oldest universities, invites applications for a Postdoctoral Researcher position in the Uhlirova Lab at the Institute for Genetics/CECAD. The lab focuses on understanding how stress-induced signaling pathways regulate gene expression and impact tissue homeostasis and ageing. This role offers an exciting opportunity to lead independent research projects using cutting-edge techniques in genetics, molecular biology, and systems biology.
Summary Table
| Category | Details |
|---|---|
| Position | Postdoctoral Researcher (f/m/x) |
| Institution | University of Cologne |
| Department | Faculty of Mathematics and Natural Sciences |
| Lab | Uhlirova Lab / Institute for Genetics / CECAD |
| Location | Cologne |
| Start Date | 1 October 2026 |
| Duration | 2 years (until 30 September 2028) |
| Working Hours | Full-time (39.83 hours/week) |
| Salary | TV-L E13 (German public sector scale) |
| Application Deadline | 15 June 2026 |
| Reference No. | Wiss2603-13 |
Designation
Postdoctoral Researcher (f/m/x)
Research Area
- Gene expression regulation
- Transcription and pre-mRNA splicing
- RNA biology and spliceosome dynamics
- Molecular and cell biology
- Genetics and functional genomics
- Ageing, tissue homeostasis, and disease mechanisms
Location
Cologne — a major academic and cultural hub in Germany with a strong international research environment.
Eligibility / Qualification
- PhD in Biology, Biochemistry, Biophysics, or related Life Sciences field
- Strong background in genetics, molecular biology, and cell biology
- Demonstrated ability to conduct independent research
- Experience with model organisms (preferably Drosophila and/or mouse)
- Excellent analytical, problem-solving, and communication skills
- Fluency in spoken and written English
- Strong teamwork and collaboration skills
Desired Skills (Assets)
- Experience in multi-omics and data analysis
- Familiarity with iPSC and/or organoid systems
- Computational modeling of protein–RNA / protein–protein interactions
- Expertise in quantitative image analysis
- Strong organizational and documentation abilities
Job Description
The selected candidate will:
- Investigate crosstalk between transcription and pre-mRNA splicing under normal and stress conditions
- Study spliceosome assembly and functional plasticity
- Identify factors influencing splicing sensitivity across transcripts, cells, and tissues
- Explore how spliceosome dysfunction affects genome stability, ageing, and disease
- Lead an independent research project while contributing to collaborative studies
- Apply advanced methods including functional genetics, multi-omics, microscopy, and bioinformatics
What We Offer
- International and collaborative research environment
- Access to state-of-the-art facilities
- Career development and advanced training opportunities
- Flexible working hours and work-life balance support
- Inclusive and diverse workplace with equal opportunity policies
How to Apply
Apply online via the official portal:
👉 https://jobportal.uni-koeln.de
Required Documents:
- Cover letter (max. 1 page) describing motivation and achievements
- Academic CV (without photo), including publications and 3 references
- Copies of degree certificates
For inquiries, contact:
Prof. Mirka Uhlirova / Dr. Esther Wollert
📧 uhlirova-jobs@uni-koeln.de
Last Date to Apply
15 June 2026
