Summary
The Department of Biomedicine at the University of Basel is seeking a dedicated Postdoctoral Researcher in Molecular Microbiology to investigate the genetic determinants of antibiotic tolerance in Mycobacterium abscessus. This role is part of an international consortium aimed at advancing our understanding of drug tolerance in challenging bacterial pathogens.
Postdoctoral Position in Molecular Microbiology, University of Basel, Switzerland
Designation
Postdoctoral Researcher
Table
| Field | Details |
|---|---|
| Research Area | Molecular Microbiology |
| Location | University of Basel, Switzerland |
| Eligibility/Qualification | – PhD in Molecular Biology, Microbiology, or related discipline – Expertise in molecular bacteriology (CRISPRi, genetic manipulation) – Basic programming skills (Python or R) – Ability to design and execute experiments independently – Strong motivation and drive – Ability to work collaboratively and mentor junior researchers – Advantageous: experience with mycobacteria, high-content imaging, and screening approaches |
Job Description
As a Postdoctoral Researcher, you will:
- Generate and screen pooled CRISPRi libraries across various M. abscessus genetic backgrounds and infection-relevant conditions.
- Utilize viability-based selection strategies to quantify bacterial killing at scale.
- Integrate results with genomic data from over 1,000 clinical isolates to develop predictive models linking genotypes to tolerance phenotypes and clinical outcomes.
- Lead the project and co-supervise a PhD student.
You will have access to cutting-edge technologies and be positioned to reshape the understanding of antibiotic efficacy.
How to Apply
To apply, please upload a single PDF that includes:
- A motivation letter
- A CV
- Contact details for at least two references
- A short description of a project you would like to pursue
Applications will be reviewed on a rolling basis until the position is filled.
Last Date to Apply
Application review will start immediately and continue until the position is filled.
For more details, visit www.unibas.ch.








