Summary
Karolinska Institutet is offering a PhD position in the Rydén and Mejhert Laboratory focusing on the role of post-transcriptional gene regulation in metabolic health and disease. This position provides a unique opportunity to engage in cutting-edge translational research that connects basic science to clinical applications.
Doctoral (PhD) Student Position in Adipocyte Systems Biology, Stockholm, Sweden
Designation
Doctoral (PhD) Student
Research Area
Adipocyte Systems Biology, focusing on human white adipose tissue and its implications in cardiometabolic disorders.
Location
Stockholm, Sweden (Karolinska Institutet, Biomedicum and Karolinska University Hospital, Huddinge)
| Category | Details |
|---|---|
| Type of Employment | PhD placement |
| Contract Type | Full-time |
| Full-time Equivalent | 100% |
| Number of Positions | 1 |
| First Day of Employment | As agreed |
| Reference Number | STÖD 2-1980/2026 |
Eligibility/Qualification
General Eligibility Requirements:
- A second-cycle/advanced/master qualification (Master’s degree).
- Alternatively, at least 240 credits, with a minimum of 60 in advanced/second-cycle/master level.
Specific Eligibility Requirement:
- Proficiency in English equivalent to Swedish upper secondary school English B/English 6.
Job Description
The doctoral project aims to:
- Investigate how alternative polyadenylation (APA) affects gene expression in adipose tissue.
- Utilize single-cell RNA sequencing to analyze APA dynamics.
- Develop computational models to study transcript isoform selection.
- Conduct functional assays to link alterations in APA to metabolic functions in human adipocytes.
The candidate will receive training in:
- Bioinformatics, single-cell data analysis, experimental techniques including human cell culture, gene perturbation methods, and metabolic phenotyping.
How to Apply
Submit your application and supporting documents through the Varbi recruitment system. Include:
- A personal letter and CV
- Degree projects and previous publications
- Documentation of eligibility (general and specific)
Last Date for Application
05 June 2026
For more information, you may contact:
- HR Partner: Anna Heinerö (anna.heinero@ki.se)
- Professor: Mikael Rydén (mikael.ryden@ki.se)
- Senior Researcher: Niklas Mejhert (niklas.mejhert@ki.se)
