The Simonetti Lab at Johns Hopkins University in Baltimore is seeking two postdoctoral fellows interested in developing new therapeutic interventions to eliminate HIV-1 reservoirs. The project will focus on the role of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in inducing CARDS-inflammasome sensing of HIV-1 Protease activity and death of infected cells by pyroptosis. The postdoc will gain expertise in the entire spectrum of HIV-1/host interactions, from molecular virology to innate and adaptive immunity. The lab is committed to recruiting scientists from underrepresented backgrounds, within and outside the US.
Summary Table:
Scholarship Title | Postdoctoral Position in HIV-1 Cure Research at Johns Hopkins University |
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Study Area | HIV-1 Cure Research |
Scholarship Description | The project will focus on the role of NNRTIs in inducing CARDS-inflammasome sensing of HIV-1 Protease activity and death of infected cells by pyroptosis. The postdoc will gain expertise in the entire spectrum of HIV-1/host interactions. |
Eligibility | Ph.D. in biology, virology, immunology, pharmacology, or related field |
Required Documents | Cover letter, Curriculum vitae, Name and contact information of three academic references |
How to Apply | Send a single pdf containing all application materials to fsimonetii@ihmi.edu |
Last Date | Applications will be accepted until the job position is filled |
Scholarship Description: The Simonetti Lab is seeking two postdoctoral fellows interested in developing new therapeutic interventions to eliminate HIV-1 reservoirs. The project will focus on the role of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) in inducing CARDS-inflammasome sensing of HIV-1 Protease activity and death of infected cells by pyroptosis, as recently discovered by Wang et al., Science 2021. The postdoc will work on integrating assays ex vivo on primary cells from people with HIV-1, animal models, and samples from clinical trials. The lab is committed to recruiting scientists from underrepresented backgrounds, within and outside the US, and will sponsor J1 visas.
Eligibility: The scholarship is open to candidates who hold a Ph.D. in biology, virology, immunology, pharmacology, or a related field. The candidate should have experience in primary cell culture, flow cytometry, and cell sorting, quantification of rare DNA or RNA targets from clinical samples, molecular biology, and sequence analysis. Programming skills in R and Python are also required.
Required Documents: Interested candidates should submit a cover letter detailing their previous research and interest in the lab, a curriculum vitae, and the name and contact information of three academic references.
How to Apply: To apply for the scholarship, candidates should send a single pdf containing all application materials to fsimonetii@ihmi.edu.
Last Date: Applications will be accepted until the job position is filled, and the scholarship is immediately available.