PhD Positions on Epigenetic Deregulation: The Department of Experimental Hematology is offering two exciting PhD positions funded by the Dutch Cancer Society. We are seeking passionate and motivated researchers to investigate the role of BCOR and BCORL1 mutations in Acute Myeloid Leukemia (AML). This project involves exploring how BCOR/L1 loss-of-function mutations impact healthy hematopoietic stem cells and their paradoxical oncogenic properties in established AML cells. Join us in contributing to cutting-edge research in the field of epigenetics and leukemia.
Table:
| Designation | Research Area | Location | Eligibility/Qualification |
|---|---|---|---|
| PhD Positions | Epigenetic deregulation in Acute Myeloid Leukemia | Department of Experimental Hematology | – MSc degree in biomedical/life sciences |
| – Strong English writing and presentation | |||
| skills | |||
| – Strong team player with independent work | |||
| capability | |||
| – Experience in cell biology (tissue culture) | |||
| – Proficiency in epigenetic techniques and NGS | |||
| data processing (preferred) | |||
| – Willingness to generate mouse models |
Job Description:
PhD Positions on Epigenetic Deregulation in Acute Myeloid Leukemia
As a PhD researcher in our team, you will investigate the mechanisms by which BCOR and BCORL1 mutations contribute to the development and progression of AML. This project will involve cutting-edge techniques, including CRISPR-Cas gene editing in primary hematopoietic cells, in-depth molecular pathway analysis, and in vivo studies using xenograft mouse models. You will work in a collaborative and dynamic research environment, contributing to ongoing efforts to understand epigenetic regulation in leukemia.
How to Apply: Interested candidates are invited to apply through our digital application form at the bottom of this page. Only applications submitted through this form will be processed. The deadline for applications is October 3, 2023. Upon submitting the digital application form, you will receive a confirmation email with further details.
Closing Date for Applications: October 3, 2023
Work Hours: 36 hours per week
Salary: €2,789 – €3,536 gross per month (scale PRO)
Contract Duration: Initially 1 year, with the possibility of extension to 3 years based on progress and successful completion of the PhD project.
Benefits: In addition to the salary, you will receive 8% holiday pay and an 8.3% end-of-year bonus. The employment conditions comply with the Collective Labour Agreement for Medical Centres (CAO-UMC).
Contact Information:
- Dr. Vincent van den Boom, Senior Scientist
- Email: [Email Address]
- Phone: +31 50 361 1244
Join us in unraveling the mysteries of epigenetic deregulation in AML and make a meaningful contribution to cancer research. We look forward to receiving your application!
Join us 